Polygala boliviensis is found in the Brazilian semiarid region. This specie is little chemically
and biologically studied. Polygala spp. have different metabolites, especially coumarins …

Background Malaria remains the major health problem responsible for many mortality and
morbidity in developing countries. Because of the development of resistance by Plasmodium …

Plasmodium species, which are spread by female Anopheles mosquitoes, are responsible
for malaria. Out of the five major Plasmodium species, Plasmodium falciparum and …

Antimicrobial resistance is a major challenge militating against the health of people globally.
Plasmodium falciparum has developed resistance to current drugs used in tackling malaria …

Many natural products have been shown to possess antiplasmodial activities, but their
protein targets are unknown. This work employed molecular docking and molecular …

The emergence of varying levels of resistance to currently available antimalarial drugs
significantly threatens global health. This factor heightens the urgency to explore bioactive …

Background The search for new antimalarial drugs remains elusive prompting research into
antimalarial combinations from medicinal plants due to their cheapness, efficacy and …

Resistance of malaria parasites to antimalarial drugs is a huge public health concern. Partial
resistance of Plasmodium falciparum to artemisinin has been reported in many malaria …

Malaria is a life-threatening infectious disease with an estimated 229 million cases in the
year 2019 worldwide. Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate …

S-adenosyl-L-homocysteine hydrolase of Plasmodium falciparum (PfSAHH) is a potential
drug target against malaria, and selective inhibition of PfSAHH is the excellent strategy to …