Epigenetic mechanisms mediating expression of the Runt-related transcription factor Runx2
are critical for controlling its osteogenic activity during skeletal development. Here, we …

Epigenetic mechanisms mediating expression of the Runt‐related transcription factor Runx2
are critical for controlling its osteogenic activity during skeletal development. Here, we …

The runt homology transcription factor Runx2/Cbfa1 is essential for bone development and
osteoblast differentiation. Regulatory mechanisms that govern Runx2 transcription in …

Runt-related transcription factor 2 (RUNX2) is a transcription factor closely associated with
the osteoblast phenotype. While frequently referred to, the complexity of its regulation and its …

RUNX2 is a transcription factor that is first expressed in early osteoblast-lineage cells and
represents a primary determinant of osteoblastogenesis. While numerous target genes are …

The Runt-related transcription factor, Runx2, is essential for osteogenesis and is controlled
by both distal (P1) and proximal (P2) promoters. To understand Runx2 function requires …

The Runt-related transcription factor 2 (Runx2) gene encodes the transcription factor Runx2,
which is the master regulator of osteoblast development; insufficiency of this protein causes …

Runt‐related transcription factor 2 (Runx2) has been shown to regulate osteoblast
differentiation by directly or indirectly regulating numerous osteoblast‐related genes …

Runx2 is essential for osteoblast development and proper bone formation. A member of the
Runt domain family of transcription factors, Runx2 binds specific DNA sequences to regulate …

Runx2, a member of the Runt domain family, is a well-known master transcription factor for
osteoblast differentiation. Runx2 has also been shown to play essential roles during …