Computational investigation of four isoquinoline alkaloids against polycystic ovarian syndrome

MK Moka - Journal of Biomolecular Structure and Dynamics, 2024 - Taylor & Francis
Hyperandrogenism, insulin resistance, and estrogen dominance are the prime defining traits
of women with polycystic ovarian syndrome which disrupts hormonal, adrenal, or ovarian …

Network pharmacology and molecular docking study of the active ingredients in Saptasaram kashayam for the treatment of Polycystic ovary syndrome

T Santh Rani, P Premitha Rajya Lakshmi… - Indian Journal of …, 2023 - op.niscpr.res.in
Abstract Polycystic Ovary Syndrome (PCOS) is one of the most prevalent endocrine disorder
in women of reproductive age characterized by hyperandrogenism (HA). Current treatment …

Computational screening of FDA-approved drugs to identify potential aromatase receptor inhibitors for polycystic ovary syndrome

F Koohnavard, K Ahmadi, E Eftekhar… - Journal of …, 2023 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is the most common cause of infertility without ovulation.
Aromatase inhibitors were first proposed as new ovulation-inducing drugs in anovulatory …

Fennel treatment to PCOS: An insilico evaluation to explore the therapeutic efficacy of anethole

A Chandran, NJ Merlin, L Ammu… - Research Journal of …, 2019 - indianjournals.com
Polycystic ovary syndrome (PCOS) or polycystic ovary disease (PCOD) is an extremely most
common endocrine and metabolic disorder recognized as the primary cause of infertility …

[HTML][HTML] Piperine's potential in treating polycystic ovarian syndrome explored through in-silico docking

R Francis, R Kalyanaraman, V Boominathan… - Scientific Reports, 2024 - nature.com
Abstract Polycystic Ovarian Syndrome (PCOS) is a multifaceted metabolic and hormonal
condition that impacts women in their procreative ages, identified by ovarian dysfunction …

Aromatase inhibitors identified from Saraca asoca to treat infertility in women with polycystic ovary syndrome via in silico and in vivo studies

K Himaja, K Veerapandiyan, B Usha - Journal of Biomolecular …, 2024 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a widely occurring metabolic disorder causing
infertility in 70%–80% of the affected women. Saraca asoca, an ancient medicinal herb, has …

Pharmacoinformatics study of Piperolactam A from Piper betle root as new lead for non steroidal anti fertility drug development

SA Amin, P Bhattacharya, S Basak, S Gayen… - … biology and chemistry, 2017 - Elsevier
Fertility control is a burning problem all over the world to regulate population overflow and
maintain ecological balance. This study is an in-silico approach to explore a non-steroidal …

Molecular docking, ADMET analysis and dynamics approach to potent natural inhibitors against sex hormone binding globulin in male infertility

MYJ Esther, V Subramaniyan, AP Kumar… - Pharmacognosy …, 2017 - phcogj.com
Objectives: The Sex Hormone Binding Globulin (SHBG) plays an important role in male
infertility. Methods: The present research computationally emphases to SHBG protein with …

The efficacy of Linum usitatissimum seeds to inhibit estrogen receptor as a natural therapy for PCOS: An in silico and in vitro analysis

F Ahmad, A Ahmed, A Shakeel… - Cell Biochemistry …, 2024 - Wiley Online Library
Polycystic ovarian syndrome (PCOS) is an endocrinological disorder aroused due to
hormonal disturbances. It is characterized by anovulation due to an excess of androgen and …

Molecular modeling studies of natural inhibitors of androgen signaling in prostate cancer

SO Olubode, MO Bankole, PA Akinnusi… - Cancer …, 2022 - journals.sagepub.com
Prostate cancer is the second most common disease in men and the sixth leading cause of
death from cancer globally, with 20 million men expected to be affected by 2024 thus …