Due to the large extent to which important biological mechanisms are conserved
evolutionarily, the study of a simple soil nematode, C. elegans, has provided the template for …

Since its introduction in 1960's, the model organism Caenorhabditis elegans has played a
crucial role towards scientific discoveries because of its relatively simple anatomy …

The nematode Caenorhabditis elegans is a powerful model organism that has been widely
used to study molecular biology, cell development, neurobiology, and aging. Despite their …

The nematode Caenorhabditis elegans is widely used as a model organism in the field of
neurobiology. The wiring of the C. elegans nervous system has been entirely mapped, and …

Most visual screens based on fluorescent markers are currently limited in throughput and
accuracy. Here we present the first genetic screen of a mutagenized population of C …

For the nematode Caenorhabditis elegans, automated selection of animals of specific
genotypes from a mixed pool has become essential for genetic interaction or chemical …

The in vivo analysis of a model organism, such as the nematode Caenorhabditis elegans,
enables fundamental biomedical studies, including development, genetics, and …

Abstract Background The nematode Caenorhabditis elegans is widely used for the genetic
analysis of neuronal cell biology, development, and behavior. Because traditional methods …

Background Advances in automated image-based microscopy platforms coupled with high-
throughput liquid workflows have facilitated the design of large-scale screens utilising …

Microscopy, phenotyping and visual screens are frequently applied to model organisms in
combination with genetics. Although widely used, these techniques for multicellular …