Oligodendrocytes in central nervous system diseases: the effect of cytokine regulation

C Zhang, M Qiu, H Fu - Neural Regeneration Research, 2024 - journals.lww.com
Cytokines including tumor necrosis factor, interleukins, interferons, and chemokines are
abundantly produced in various diseases. As pleiotropic factors, cytokines are involved in …

Oligodendrocytes in development, myelin generation and beyond

S Kuhn, L Gritti, D Crooks, Y Dombrowski - Cells, 2019 - mdpi.com
Oligodendrocytes are the myelinating cells of the central nervous system (CNS) that are
generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the …

Developmental stage of oligodendrocytes determines their response to activated microglia in vitro

BA Miller, JM Crum, CA Tovar, AR Ferguson… - Journal of …, 2007 - Springer
Abstract Background Oligodendrocyte progenitor cells (OPCs) and mature oligodendrocytes
are both lost in central nervous system injury and disease. Activated microglia may play a …

Not only myelination: the immune-inflammatory functions of oligodendrocytes

M Boccazzi, S Raffaele… - Neural Regeneration …, 2022 - journals.lww.com
Oligodendrocytes (OLs) are highly specialized cells of the central nervous system (CNS).
Their primary and most investigated role is to form myelin, a multilamellar fatty membrane …

[PDF][PDF] Neuroinflammatory modulators of oligodendrogenesis

A Armada-Moreira, FF Ribeiro… - Neuroimmunol …, 2015 - researchgate.net
Oligodendrocytes are key neural cells that are responsible for producing myelin sheaths that
wrap around neuronal axons in the central nervous system. Myelin is essential to insulate …

Oligodendrocyte‐microglia cross‐talk in the central nervous system

L Peferoen, M Kipp, P van der Valk, JM van Noort… - …, 2014 - Wiley Online Library
Communication between the immune system and the central nervous system (CNS) is
exemplified by cross‐talk between glia and neurons shown to be essential for maintaining …

Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation

DL Schonberg, PG Popovich… - … of Neuropathology & …, 2007 - academic.oup.com
Oligodendrocytes are vulnerable to CNS injury and disease. Because oligodendrocytes
myelinate CNS axons, their death leads to demyelination and impaired axon conductance …

Oligodendrocyte physiology and pathology function

M Kipp - Cells, 2020 - mdpi.com
The adult vertebrate central nervous system (CNS) mainly consists of neurons, astrocytes,
microglia cells and oligodendrocytes. Oligodendrocytes, the myelin-forming cells of the …

Oligodendroglia and myelin in neurodegenerative diseases: more than just bystanders?

B Ettle, JCM Schlachetzki, J Winkler - Molecular neurobiology, 2016 - Springer
Oligodendrocytes, the myelinating cells of the central nervous system, mediate rapid action
potential conduction and provide trophic support for axonal as well as neuronal …

The immunomodulatory oligodendrocyte

T Zeis, L Enz, N Schaeren-Wiemers - Brain research, 2016 - Elsevier
Oligodendrocytes, the myelinating glial cells of the central nervous system (CNS), are due to
their high specialization and metabolic needs highly vulnerable to various insults. This led to …