Could gene therapy cure HIV?

M Sheykhhasan, A Foroutan, H Manoochehri… - Life Sciences, 2021 - Elsevier
Abstract The Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome
(AIDS) continues to be a major global public health issue, having claimed almost 33 million …

Potential mechanisms for cell-based gene therapy to treat HIV/AIDS

E Herrera-Carrillo, B Berkhout - Expert opinion on therapeutic …, 2015 - Taylor & Francis
Introduction: An estimated 35 million people are infected with HIV worldwide. Anti-retroviral
therapy (ART) has reduced the morbidity and mortality of HIV-infected patients but efficacy …

Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS

J Chung, DL DiGiusto, JJ Rossi - Expert opinion on biological …, 2013 - Taylor & Francis
Introduction: HIV/AIDS continues to be a worldwide health problem and viral eradication has
been an elusive goal. HIV+ patients are currently treated with combination antiretroviral …

Fight fire with fire: Gene therapy strategies to cure HIV

J Huyghe, S Magdalena… - Expert Review of Anti …, 2017 - Taylor & Francis
ABSTRACT Introduction: Human Immunodeficiency Virus (HIV) to date remains one of the
most notorious viruses mankind has ever faced. Despite enormous investments in HIV …

[HTML][HTML] Advances in HIV Gene Therapy

R Kitawi, S Ledger, AD Kelleher… - International Journal of …, 2024 - mdpi.com
Early gene therapy studies held great promise for the cure of heritable diseases, but the
occurrence of various genotoxic events led to a pause in clinical trials and a more guarded …

[PDF][PDF] Gene therapy for HIV-1 infection: are lethal genes a valuable tool

F Luque, R Oya, D Macias, L Saniger - Cell Mol Biol, 2005 - researchgate.net
At present, virus replication is quite efficiently blocked by highly active antiretroviral therapy
(HAART). However current HAART therapies still have important limitations that compromise …

Gene therapy: a possible future standard for HIV care

M Abou-El-Enein, G Bauer, P Reinke - Trends in Biotechnology, 2015 - cell.com
Despite undeniable accomplishments in developing cell and gene therapeutic strategies to
combat HIV infection, key social, economic, and policy-related challenges still need to be …

Gene therapy for HIV infection

C de Mendoza, P Barreiro, L Benitez… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Highly active antiretroviral therapy has been the big paradigm for transforming
HIV infection in a chronic disease. However, it requires lifelong administration as the HIV …

HIV Gene Therapy Strategies and Safety: What do we know from the Recent Publications?

SD Zaongo, H Xia, P Ma - AIDS reviews, 2020 - search.ebscohost.com
Almost 40 years ago, the world was noticing the emergence of one of the major public health
threats it has ever known: HIV. Facing the cost-effectiveness and the health-related issues …

Gene therapy for HIV-1 infection

L Egerer, D von Laer, J Kimpel - Recent Translational Research …, 2011 - books.google.com
The introduction of the highly active antiretroviral therapy (HAART) for the treatment of HIV-1-
infection has dramatically improved the quality of life and the survival of HIV-infected …