The fructose survival hypothesis for obesity

RJ Johnson, MA Lanaspa… - … of the Royal …, 2023 - royalsocietypublishing.org
The fructose survival hypothesis proposes that obesity and metabolic disorders may have
developed from over-stimulation of an evolutionary-based biologic response (survival …

The fructose survival hypothesis as a mechanism for unifying the various obesity hypotheses

RJ Johnson, LG Sánchez‐Lozada, MA Lanaspa - Obesity, 2024 - Wiley Online Library
The pathogenesis of obesity remains contested. Although genetics is important, the rapid
rise in obesity with Western culture and diet suggests an environmental component. Today …

Fructose metabolism as a common evolutionary pathway of survival associated with climate change, food shortage and droughts

RJ Johnson, P Stenvinkel, P Andrews… - Journal of Internal …, 2020 - Wiley Online Library
Mass extinctions occur frequently in natural history. While studies of animals that became
extinct can be informative, it is the survivors that provide clues for mechanisms of adaptation …

Carbohydrate-insulin model: does the conventional view of obesity reverse cause and effect?

DS Ludwig - … Transactions of the Royal Society B, 2023 - royalsocietypublishing.org
Conventional obesity treatment, based on the First Law of Thermodynamics, assumes that
excess body fat gain is driven by overeating, and that all calories are metabolically alike in …

F stands for fructose and fat

CA Lyssiotis, LC Cantley - Nature, 2013 - nature.com
F stands for fructose and fat | Nature Skip to main content Thank you for visiting nature.com.
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[HTML][HTML] Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?

RJ Johnson, DR Tolan, D Bredesen, M Nagel… - The American Journal of …, 2023 - Elsevier
An important aspect of survival is to assure enough food, water, and oxygen. Here, we
describe a recently discovered response that favors survival in times of scarcity, and it is …

[HTML][HTML] Fructose: it's “alcohol without the buzz”

RH Lustig - Advances in nutrition, 2013 - Elsevier
Abstract What do the Atkins Diet and the traditional Japanese diet have in common? The
Atkins Diet is low in carbohydrate and usually high in fat; the Japanese diet is high in …

Fructose: metabolic, hedonic, and societal parallels with ethanol

RH Lustig - Journal of the American Dietetic Association, 2010 - Elsevier
Rates of fructose consumption continue to rise nationwide and have been linked to rising
rates of obesity, type 2 diabetes, and metabolic syndrome. Because obesity has been …

Fructose vs. glucose and metabolism: do the metabolic differences matter?

JL Sievenpiper, RJ de Souza, AI Cozma… - Current Opinion in …, 2014 - journals.lww.com
Fructose vs. glucose and metabolism: do the metabolic differ... : Current Opinion in
Lipidology Fructose vs. glucose and metabolism: do the metabolic differences matter …

Fructose: should we worry?

GA Bray - International journal of obesity, 2008 - nature.com
Obesity is a growing problem. In the broadest strokes, it is due to a small positive energy
balance that persists over a sufficiently long time. Some forms of obesity develop …