In Vitro Experiments Demonstrate that Monocytes and Dendritic Cells are Rendered Apoptotic by Extracorporeal Photochemotherapy, but Exhibit Unaffected …

V Rao, M Saunes, S Jørstad… - Scandinavian journal of …, 2008 - Wiley Online Library
Extracorporeal photochemotherapy (ECP) has been shown to induce apoptosis in
lymphocytes. Until recently the prevailing opinion has been that the monocytes were mainly …

Photochemotherapy induces the apoptosis of monocytes without impairing their function

D Hannani, F Gabert, D Laurin, M Sall, JP Molens… - …, 2010 - journals.lww.com
Background. Extracorporeal photopheresis (ECP) is a powerful therapy currently used to
treat various hematological disorders as in graft versus host disease. Clinical data clearly …

In vitro treatment of monocytes with 8-methoxypsolaren and ultraviolet A light induces dendritic cells with a tolerogenic phenotype

A Legitimo, R Consolini, A Failli… - Clinical & …, 2007 - academic.oup.com
Extracorporeal photopheresis (ECP) has been considered an efficient dendritic cell (DC)
therapy, used for treating both T cell malignancy, as well as T cell-mediated diseases …

Mechanisms of action of extracorporeal photochemotherapy

F Heshmati - Transfusion and apheresis science, 2003 - Elsevier
Extracorporeal photochemotherapy (ECP) has been shown to be effective in variety of
pathologic diseases such as Sezary syndrome, autoimmune diseases, organ graft rejection …

The common pathways, but different outcomes, of apoptosis induced by extracorporeal photopheresis and in vivo chemotherapy may reinforce the important …

J Bladon, P Taylor - Blood, The Journal of the American Society …, 2002 - ashpublications.org
11. Vowels B, Cassin M, Boufal M, Walsh L, Rook A. Extracorporeal photochemotherapy
induces the production of tumour necrosis factor-α by monocytes: implications for the …

Photochemotherapy induces a faster apoptosis of alloreactive activated T cells than of nonalloreactive resting T cells in graft versus host disease

D Hannani, E Merlin, F Gabert, D Laurin… - …, 2010 - journals.lww.com
Background. Graft versus host disease (GvHD) is the main complication after hematopoietic
stem-cell transplantation. Extracorporeal photochemotherapy (ECP) is a cell therapy …

Extracorporeal photochemotherapy (photopheresis) induces apoptosis in lymphocytes: a possible mechanism of action of PUVA therapy

DNH Enomoto, PTA Schellekens… - Photochemistry and …, 1997 - Wiley Online Library
The mechanism of action of psoralen plus UVA (PUVA) and photopheresis is not entirely
understood. These therapies are assumed to be immunomodulating partly by gradually …

Cryopreservation of mononuclear cells before extracorporeal photochemotherapy does not impair their anti-proliferative capabilities

E Merlin, D Hannani, R Veyrat-Masson, J Chassagne… - …, 2011 - Taylor & Francis
Background aims. The clinical benefits of extracorporeal photochemotherapy (ECP) are well
recognized, but its clinical use is limited by logistical difficulties, especially because of the …

Extracorporeal photopheresis: a focus on apoptosis and cytokines

J Bladon, PC Taylor - Journal of dermatological science, 2006 - Elsevier
Induction of apoptosis and changes to cytokine secretion patterns have been implicated in
the mechanism of action of extracorporeal photopheresis (ECP). Lymphocyte apoptosis is …

Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy

C Berger, K Hoffmann, JG Vasquez… - Blood, The Journal …, 2010 - ashpublications.org
Extracorporeal photochemotherapy (ECP) is widely used to treat cutaneous T-cell
lymphoma, graft-versus-host disease, and allografted organ rejection. Its clinical and …