[HTML][HTML] An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
[HTML][HTML] Zika virus NS5 protein antagonizes type I interferon production via blocking TBK1 activation
Zika virus (ZIKV) is a mosquito-borne positive-sense single-stranded RNA virus in the family
of Flaviviridae. Unlike other flaviviruses, ZIKV infection of pregnant women may result in birth …
of Flaviviridae. Unlike other flaviviruses, ZIKV infection of pregnant women may result in birth …
[HTML][HTML] Zika virus NS3 mimics a cellular 14-3-3-binding motif to antagonize RIG-I-and MDA5-mediated innate immunity
3-3 protein family members facilitate the translocation of RIG-I-like receptors (RLRs) to
organelles that mediate downstream RLR signaling, leading to interferon production. 14-3 …
organelles that mediate downstream RLR signaling, leading to interferon production. 14-3 …
Zika virus proteins NS2A and NS4A are major antagonists that reduce IFN-β promoter activity induced by the MDA5/RIG-I signaling pathway
NTT Ngan, SJ Kim, JY Lee… - Journal of microbiology …, 2019 - koreascience.kr
Zika virus (ZIKV) is a mosquito-transmitted, emerging Flavivirus that causes Guillain-$ Barr
{\acute {e}} $ syndrome and microcephaly in adults and fetuses, respectively. Since ZIKV …
{\acute {e}} $ syndrome and microcephaly in adults and fetuses, respectively. Since ZIKV …
Selective activation of type II interferon signaling by Zika virus NS5 protein
Severe complications of Zika virus (ZIKV) infection might be caused by inflammation, but
how ZIKV induces proinflammatory cytokines is not understood. In this study, we show …
how ZIKV induces proinflammatory cytokines is not understood. In this study, we show …
[HTML][HTML] Evolution of two major Zika virus lineages: implications for pathology, immune response, and vaccine development
Zika virus (ZIKV) became a public health emergency of global concern in 2015 due to its
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …
[HTML][HTML] Zika virus targets human STAT2 to inhibit type I interferon signaling
The ongoing epidemic of Zika virus (ZIKV) illustrates the importance of flaviviruses as
emerging human pathogens. All vector-borne flaviviruses studied thus far have to overcome …
emerging human pathogens. All vector-borne flaviviruses studied thus far have to overcome …
[HTML][HTML] Zika virus antagonizes type I interferon responses during infection of human dendritic cells
JR Bowen, KM Quicke, MS Maddur, JT O'Neal… - PLoS …, 2017 - journals.plos.org
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that is causally linked to severe
neonatal birth defects, including microcephaly, and is associated with Guillain-Barre …
neonatal birth defects, including microcephaly, and is associated with Guillain-Barre …
[HTML][HTML] Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro
Type I interferon (IFN) serves as the first line of defense against invading pathogens.
Inhibition of IFN-triggered signaling cascade by Zika virus (ZIKV) plays a critical role for ZIKV …
Inhibition of IFN-triggered signaling cascade by Zika virus (ZIKV) plays a critical role for ZIKV …
[HTML][HTML] An immunocompetent mouse model of Zika virus infection
Progress toward understanding Zika virus (ZIKV) pathogenesis is hindered by lack of
immunocompetent small animal models, in part because ZIKV fails to effectively antagonize …
immunocompetent small animal models, in part because ZIKV fails to effectively antagonize …