Experimental ultrasonic angioplasty: disruption of atherosclerotic plaques and thrombi in vitro and arterial recanalization in vivo

U Rosenschein, JJ Bernstein, E DiSegni… - Journal of the American …, 1990 - Elsevier
To investigate the use of high energy ultrasound as an alternative energy for angioplasty, an
experimental ultrasonic angioplasty device was developed. The device was studied in two …

Ultrasonic angioplasty in totally occluded peripheral arteries. Initial clinical, histological, and angiographic results.

U Rosenschein, LA Rozenszajn, L Kraus, CC Marboe… - Circulation, 1991 - Am Heart Assoc
BACKGROUND Ultrasonic angioplasty was recently shown to ablate thrombi and
atherosclerotic plaques in vitro and to recanalize occluded arteries in experimental animal …

Ultrasonic plaque ablation. A new method for recanalization of partially or totally occluded arteries.

RJ Siegel, MC Fishbein, J Forrester, K Moore… - Circulation, 1988 - Am Heart Assoc
The potential application of ultrasonic energy for ablation of atherosclerotic plaques was
studied in human atherosclerotic arteries with continuous and pulsed delivery of energy …

Study of the mechanism of ultrasound angioplasty from human thrombi and bovine aorta

U Rosenschein, A Frimerman, S Laniado… - The American journal of …, 1994 - Elsevier
Ultrasound angioplasty is a newly developed technology for percutaneous arterial
recanalization. Data suggest that ultrasound is particularly effective in ablating fresh thrombi …

Ultrasonic energy. Effects on vascular function and integrity.

TA Fischell, MA Abbas, GW Grant, RJ Siegel - Circulation, 1991 - Am Heart Assoc
BACKGROUND Ultrasonic energy transmitted via flexible wire probes provides a new
means of ablating atherosclerotic plaque. We studied the effects of ultrasonic energy (20 …

In vivo ultrasound arterial recanalization of atherosclerotic total occlusions

RJ Siegel, TA DonMichael, MC Fishbein… - Journal of the American …, 1990 - Elsevier
The purpose of this study was to assess the potential of intraarterial ultrasound for in vivo
recanalization of atherosclerotic total occlusions. Ultrasound energy at a frequency of 20 …

Ability of high-intensity ultrasound to ablate human atherosclerotic plaques and minimize debris size

A Ernst, EA Schenk, SM Gracewski… - The American journal of …, 1991 - Elsevier
To investigate whether high-intensity ultrasound can destroy atherosclerotic plaques while
sparing the normal arterial wall, 279 normal human aortic sites and 119 fibrous and 193 …

Percutaneous ultrasonic angioplasty: initial clinical experience

RJ Siegel, RK Myler, DC Cumberland, TA Donmichael - The Lancet, 1989 - Elsevier
Percutaneous catheter-delivered ultrasound energy for arterial recanalisation was applied in
eight patients with peripheral vascular disease. Four patients had severe claudication with …

Effects of ultrasound energy on thrombi in vitro

F Philippe, G Drobinski, C Bucherer… - Catheterization and …, 1993 - Wiley Online Library
Ultrasonic energy may be used for dissolution of venous or arterial thrombi. However, its
effects may depend on the mode of ultrasonic vibration and on the length of the probe. We …

Use of therapeutic ultrasound in percutaneous coronary angioplasty. Experimental in vitro studies and initial clinical experience.

RJ Siegel, J Gunn, A Ahsan, MC Fishbein, RJ Bowes… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Previous studies have shown the feasibility of peripheral arterial ultrasound
angioplasty. METHODS AND RESULTS In this report, we describe the use of percutaneous …