The vessel wall is composed of distinct cellular layers, yet communication among individual
cells within and between layers results in a dynamic and versatile structure. The …

The assembly of the vessel wall from its cellular and extracellular matrix components is a
critical process in the development and maturation of the cardiovascular system. However …

Research into areas as divergent as hemangiopoiesis and cardiogenesis as well as
investigations of diseases such as cancer and diabetic retinopathy have converged to form …

There are two vascular networks in mammals that coordinately function as the main supply
and drainage systems of the body. The blood vasculature carries oxygen, nutrients …

Formation of new blood vessels is vital during embryogenesis, essential for reproduction
and wound healing during adulthood, and required to rescue tissue during ischemia …

▪ Abstract The vasculature is one of the most important and complex organs in the
mammalian body. The first functional organ to form during embryonic development, the …

Endothelial and smooth muscle cells interact with each other to form new blood vessels. In
this review, the cellular and molecular mechanisms underlying the formation of endothelium …

Endothelial cells display an extraordinary plasticity both during development and throughout
adult life. During early development, endothelial cells assume arterial, venous, or lymphatic …

Blood and lymphatic vessels pervade almost all body tissues and have numerous essential
roles in physiology and disease. The inner lining of these networks is formed by a single …

The vasculature plays an indispensible role in organ development and maintenance of
tissue homeostasis, such that disturbances to it impact greatly on developmental and …