Objective Ischemic stroke is known as a neurodegenerative disorder, which induces long‐
period tissue damage. Chemokine (C–X–C motif) ligand 8 (CXCL8) is involved in acute …

Inflammatory processes have a detrimental role in the pathophysiology of ischemic stroke.
However, little is known about the endogenous anti-inflammatory mechanisms in ischemic …

Background and Purpose—Inflammatory response plays a critical role in propagating tissue
damage after focal cerebral ischemia. CXCL12 is a key chemokine for leukocyte recruitment …

Identification of specific biomarkers for ischemic stroke is necessary due to their abilities to
improve treatment outcomes. Many studies have demonstrated the involvement of …

Background Chronic cerebral ischemia induces white matter injury (WMI) contributing to
cognitive decline. Both astrocytes and microglia play vital roles in the demyelination and …

Granulocytes and natural killer (NK) cells have been linked to brain injury in ischemic stroke.
However, their recruitment from peripheral leucocytes in stroke patients is not well …

Background Inflammation plays a key role in the pathophysiology of ischemic stroke. Some
proinflammatory mediators, such as cytokines and chemokines, are produced in stroke …

Background: Stroke is the second leading cause of death and a major cause of disability of
adults worldwide. Inflammatory processes are known to contribute to the pathophysiology of …

Abstract Aims Chemokine receptor 7 (CXCR7) exerts protective effects on the brain.
MicroRNAs (miRNAs) are involved in cerebral ischemia/reperfusion (I/R) injury, but their …

Chemokine CXC ligand 12 (CXCL12), originally named stromal cell-derived factor-1 (SDF-
1), is a member of the CXC chemokine subfamily. CXCL12 is found to be expressed by all …