Vitamin B6 may alleviate diabetes by regulating insulin secretion and increasing insulin
sensitivity, but its mechanism remains to be explored. In this study, vitamin B6-mediated …

Epidemiological evidence indicates that vitamin D is involved in defense against diabetes;
however, the precise underlying mechanism remains to be elucidated. In the present study …

Vitamin D deficiency is considered a pandemic and has been postulated to increase the risk
of type 2 diabetes mellitus (T2DM). Activation of nod-like receptor protein 3 (NLRP3) …

Diabetes mellitus is a serious disease endangering human health worldwide. Vitamin D (Vit
D) is a well-characterized regulator of calcium-phosphorus metabolism that also exerts other …

Diabetes mellitus is a leading cause of death and disability worldwide, which presents a
serious public health crisis in China nowadays. It has been well recognized that excessive β …

Lipotoxicity of pancreatic β-cells is the pathological manifestation of obesity-linked type II
diabetes. We intended to determine the cytoprotective effect of kaempferol on pancreatic β …

Objective Stimulation with saturated fatty acids has been shown to induce oxidative stress
and endoplasmic reticulum (ER) stress in β cells and has been recognized as an important …

Recent studies have demonstrated that the expression of miR‐34a is significantly
upregulated and associated with cell apoptosis in pancreatic β‐cell treated with palmitate …

Baicalin (BAI), one major flavonoid from Scutellaria baicalensis, possesses anticancer and
anti‐inflammatory properties. However, the effect of BAI on diabetes mellitus has not been …

Promoting beta-cell survival is crucial for the prevention of beta-cell failure in diabetes.
Thiazolidinediones, a widely used drug to improve insulin sensitivity in clinical practice, is …