The parafascicular nucleus (Pf) of the thalamus provides major projections to the basal
ganglia, a set of subcortical nuclei involved in action initiation. Here, we show that Pf …

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus
(GPi) is an effective treatment for parkinsonian motor signs. Though its therapeutic …

Deep brain stimulation (DBS) in the subthalamic nucleus (STN) is an effective tool for the
treatment of advanced Parkinson's disease. The mechanism by which STN DBS elicits its …

The subthalamic nucleus projects to the external and internal pallidum, the modulatory and
output nuclei of the basal ganglia, respectively, and plays an indispensable role in …

The subthalamic nucleus (STN) controls basal ganglia outputs via the substantia nigra pars
reticulata (SNr) and the globus pallidus internus (GPi). However, the synaptic properties of …

Subthalamic nucleus deep brain stimulation (STN DBS) relieves many motor symptoms of
Parkinson's disease (PD), but its underlying therapeutic mechanisms remain unclear. Since …

While high-frequency stimulation of the subthalamic nucleus (STN-HFS) is highly effective in
the treatment of Parkinson's disease (PD), the mechanisms underlying its therapeutic action …

How do we decide what we do? This is the essence of action control, the process of
selecting the most appropriate response among multiple possible choices. Suboptimal …

The degeneration of dopaminergic neurons in the substantia nigra pars compacta leads to
parkinsonian motor symptoms via changes in electrophysiological activity throughout the …

The subthalamic nucleus (STN) plays a key role in the control of voluntary movements and
basal ganglia disorders, such as Parkinson9s disease and hemiballismus. The STN …