The mutualistic association between Wolbachia endosymbionts and their filarial nematode
hosts has been exploited as a validated drug target delivering macrofilaricidal outcomes …

Lymphatic filariasis and onchocerciasis are debilitating diseases caused by parasitic filarial
nematodes infecting around 150 million people throughout the tropics with more than 1.5 …

Onchocerciasis and lymphatic filariasis are two neglected tropical diseases that together
affect∼ 157 million people and inflict severe disability. Both diseases are caused by …

Nematodes causing lymphatic filariasis and onchocerciasis rely on their bacterial
endosymbiont, Wolbachia, for survival and fecundity, making Wolbachia a promising …

Lymphatic filariasis and onchocerciasis are two important neglected tropical diseases
(NTDs) that cause severe disability. Control efforts are hindered by the lack of a safe …

Lymphatic filariasis and onchocerciasis are debilitating diseases caused by parasitic filarial
nematodes. These nematodes have evolved a mutualistic symbiosis with intracellular …

Anti-Wolbachia therapy delivers safe macrofilaricidal activity with superior therapeutic
outcomes compared to all standard anti-filarial treatments, with the added benefit of …

There is an urgent need to develop new, safe, and affordable macrofilaricidal drugs for
onchocerciasis and lymphatic filariasis treatment and control. The Anti-Wolbachia …

Lymphatic filariasis and onchocerciasis are parasitic helminth diseases, which cause severe
morbidities such as elephantiasis, skin disease and blindness, presenting a major public …

Human disease caused by parasitic filarial nematodes is a major cause of global morbidity.
The parasites are transmitted by arthropod intermediate hosts and are responsible for …