[HTML][HTML] The clinical implications of nocebo effects for biosimilar therapy
L Colloca, R Panaccione, TK Murphy - Frontiers in pharmacology, 2019 - frontiersin.org
Nocebo effects encompass negative responses to inert interventions in the research setting
and negative outcomes with active treatments in the clinical research or practice settings …
and negative outcomes with active treatments in the clinical research or practice settings …
[HTML][HTML] Treatment outcomes with biosimilars: be aware of the nocebo effect
MF Rezk, B Pieper - Rheumatology and therapy, 2017 - Springer
Over the years, biologic agents have proven their importance in the management of chronic
autoimmune diseases, such as rheumatoid arthritis, psoriasis, and inflammatory bowel …
autoimmune diseases, such as rheumatoid arthritis, psoriasis, and inflammatory bowel …
[HTML][HTML] To see or NOsee: the debate on the nocebo effect and optimizing the use of biosimilars
MF Rezk, B Pieper - Advances in therapy, 2018 - Springer
Abstract In addition to the general clinical benefit offered, biosimilars may not only generate
savings for healthcare budgets but also improve patient access to biologic products. Since …
savings for healthcare budgets but also improve patient access to biologic products. Since …
The nocebo effect: a clinical challenge in the era of biosimilars
L Pouillon, M Socha, B Demore, N Thilly… - Expert review of …, 2018 - Taylor & Francis
Introduction: The nocebo effect is defined as a negative effect of a pharmacological or non-
pharmacological medical treatment that is induced by patients' expectations, and that is …
pharmacological medical treatment that is induced by patients' expectations, and that is …
The biosimilar nocebo effect? A systematic review of double-blinded versus open-label studies
JS Odinet, CE Day, JL Cruz, GA Heindel - Journal of managed care & …, 2018 - jmcp.org
BACKGROUND: Several authors have hypothesized that adverse drug events (ADEs) upon
switching from reference biologics to biosimilar products are related to the nocebo effect …
switching from reference biologics to biosimilar products are related to the nocebo effect …
[HTML][HTML] Nonmedical switching from originators to biosimilars: does the nocebo effect explain treatment failures and adverse events in rheumatology and …
R Fleischmann, V Jairath, E Mysler, D Nicholls… - Rheumatology and …, 2020 - Springer
The act of nonmedical switching, defined as switching stable patients who are generally
doing well with their current therapy from an originator biologic to its biosimilar, has been …
doing well with their current therapy from an originator biologic to its biosimilar, has been …
[HTML][HTML] Non-pharmacological effects in switching medication: the nocebo effect in switching from originator to biosimilar agent
The nocebo effect is defined as the incitement or the worsening of symptoms induced by any
negative attitude from non-pharmacological therapeutic intervention, sham, or active …
negative attitude from non-pharmacological therapeutic intervention, sham, or active …
[HTML][HTML] European stakeholder learnings regarding biosimilars: part II—improving biosimilar use in clinical practice
Background Despite the benefits biosimilars offer in terms of cost savings and patient
access, healthcare professionals and patients have been reluctant to use them. Next to …
access, healthcare professionals and patients have been reluctant to use them. Next to …
Nocebos in rheumatology: emerging concepts and their implications for clinical practice
E Kravvariti, GD Kitas, DD Mitsikostas… - Nature reviews …, 2018 - nature.com
Nocebo effects are noxious reactions to therapeutic interventions that occur because of
negative expectations of the patient. In the past decade, neurobiological data have revealed …
negative expectations of the patient. In the past decade, neurobiological data have revealed …
Treatment journey in rheumatoid arthritis with biosimilars: from better access to good disease control through cost savings and prevention of nocebo effects
Early diagnosis and treatment of rheumatoid arthritis (RA) are of critical importance to halt
the progression of the disease. Optimal use of advanced imaging techniques or biomarkers …
the progression of the disease. Optimal use of advanced imaging techniques or biomarkers …
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