[HTML][HTML] Impact of low dose prenatal ethanol exposure on glucose homeostasis in Sprague-Dawley rats aged up to eight months

ME Probyn, KR Parsonson, EM Gårdebjer, LC Ward… - PLoS …, 2013 - journals.plos.org
Excessive exposure to alcohol prenatally has a myriad of detrimental effects on the health
and well-being of the offspring. It is unknown whether chronic low-moderate exposure of …

Prenatal alcohol exposure programmes offspring disease: insulin resistance in adult males in a rat model of acute exposure

TMT Nguyen, SE Steane, KM Moritz… - The Journal of …, 2019 - Wiley Online Library
Key points Prenatal alcohol exposure has the potential to affect fetal development and
programme chronic disease in offspring. Previous preclinical models typically use high …

Intergenerational effects of prenatal ethanol on glucose tolerance and insulin response

KM Harper, E Tunc-Ozcan, EN Graf… - Physiological …, 2014 - journals.physiology.org
Consequences of prenatal exposure to ethanol (E) include morphological, physiological,
and cognitive deficits and are collectively classified as fetal alcohol spectrum disorders …

A rodent model of low-to moderate-dose ethanol consumption during pregnancy: patterns of ethanol consumption and effects on fetal and offspring growth

ME Probyn, S Zanini, LC Ward… - Reproduction, Fertility …, 2012 - CSIRO Publishing
It is unknown whether low to moderate maternal alcohol consumption adversely affects
postnatal health. The aim of the present study was to develop a rodent model of low …

Maternal alcohol intake around the time of conception causes glucose intolerance and insulin insensitivity in rat offspring, which is exacerbated by a postnatal high‐fat …

EM Gårdebjer, ST Anderson, M Pantaleon… - The FASEB …, 2015 - Wiley Online Library
Alcohol consumption throughout pregnancy can cause metabolic dysregulation, including
glucose intolerance in progeny. This study determined if periconceptional (PC) alcohol (12 …

Chronic prenatal ethanol exposure alters expression of central and peripheral insulin signaling molecules in adult guinea pig offspring

CC Dobson, K Thevasundaram, DL Mongillo… - Alcohol, 2014 - Elsevier
Maternal ethanol consumption during pregnancy can produce a range of teratogenic
outcomes in offspring. The mechanism of ethanol teratogenicity is multi-faceted, but may …

Perinatal maternal ethanol effects on pregnant mice and on offspring viability and growth: influences of exposure time and weaning diet

LD Middaugh, WO Boggan - Alcoholism: Clinical and …, 1995 - Wiley Online Library
C57BL/6 mice were maintained on liquid diets containing 27.5% ethanol‐derived calories
beginning on gestational day 12. For one group, the liquid diet was replaced with laboratory …

Abnormal glucose homeostasis in adult female rat offspring after intrauterine ethanol exposure

XH Yao, BL Gregoire Nyomba - American Journal of …, 2007 - journals.physiology.org
Adverse events during pregnancy, including prenatal ethanol (EtOH) exposure, are
associated with insulin-resistant diabetes in male rat offspring, but it is unclear whether this …

[HTML][HTML] Chronic prenatal ethanol exposure increases adiposity and disrupts pancreatic morphology in adult guinea pig offspring

CC Dobson, DL Mongillo, DC Brien, R Stepita… - Nutrition & …, 2012 - nature.com
Background: Ethanol consumption during pregnancy can lead to a range of adverse
developmental outcomes in children, termed fetal alcohol spectrum disorder (FASD). Central …

Effects of prenatal alcohol exposure on glucose tolerance in the rat offspring

L Chen, BLG Nyomba - Metabolism, 2003 - Elsevier
Low birth weight in humans predisposes to obesity, cardiovascular diseases, and type 2
diabetes in adult life. Alcohol exposure during pregnancy has been associated with fetal …