The neural effects of oxytocin administration in autism spectrum disorders studied by fMRI: A systematic review

S Fathabadipour, Z Mohammadi, F Roshani… - Journal of psychiatric …, 2022 - Elsevier
Purpose Oxytocin (OXT) is a hypothalamic neuropeptide that is released from the posterior
pituitary gland and at specific targets in the central nervous system (CNS). The prosocial …

Clinical trial of modulatory effects of oxytocin treatment on higher-order social cognition in autism spectrum disorder: a randomized, placebo-controlled, double-blind …

K Preckel, P Kanske, T Singer, FM Paulus, S Krach - BMC psychiatry, 2016 - Springer
Background Autism spectrum disorders are neurodevelopmental conditions with severe
impairments in social communication and interaction. Pioneering research suggests that …

Oxytocin induces long-lasting adaptations within amygdala circuitry in autism: a treatment-mechanism study with randomized placebo-controlled design

K Alaerts, S Bernaerts, J Prinsen, C Dillen… - …, 2020 - nature.com
Intranasal administration of the neuropeptide oxytocin (IN-OT) is increasingly explored as a
potential treatment for targeting the core symptoms of autism spectrum disorder (ASD). To …

Neurophysiological effects of acute oxytocin administration: systematic review and meta-analysis of placebo-controlled imaging studies

R Wigton, J Radua, P Allen, B Averbeck… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: Oxytocin (OXT) plays a prominent role in social cognition and may have clinical
applications for disorders such as autism, schizophrenia and social anxiety. The neural …

Oxytocin and brain activity in humans: a systematic review and coordinate-based meta-analysis of functional MRI studies

SA Grace, SL Rossell, M Heinrichs… - …, 2018 - Elsevier
Oxytocin (OXT) is a neuropeptide which has a critical role in human social behaviour and
cognition. Research investigating the role of OXT on functional brain changes in humans …

Oxytocin and autism spectrum disorders: a systematic review and meta-analysis of randomized controlled trials

YP Ooi, SJ Weng, J Kossowsky, H Gerger… - …, 2017 - thieme-connect.com
Aim: Oxytocin presents an exciting potential to target the core symptoms of autism spectrum
disorder (ASD) pharmacologically in an easily administered, cost-effective form with possibly …

Clinical and neural effects of six-week administration of oxytocin on core symptoms of autism

T Watanabe, M Kuroda, H Kuwabara, Y Aoki… - Brain, 2015 - academic.oup.com
Autism spectrum disorder is a prevalent neurodevelopmental disorder with no established
pharmacological treatment for its core symptoms. Although previous literature has shown …

Oxytocin treatment attenuates amygdala activity in autism: a treatment-mechanism study with long-term follow-up

S Bernaerts, B Boets, J Steyaert, N Wenderoth… - Translational …, 2020 - nature.com
Intranasal administration of the neuropeptide oxytocin (IN-OT) is increasingly considered as
a potential treatment for targeting the core symptoms of autism spectrum disorder (ASD), but …

A pilot study of serotonergic modulation after long‐term administration of oxytocin in autism spectrum disorder

T Hirosawa, M Kikuchi, Y Ouchi, T Takahashi… - Autism …, 2017 - Wiley Online Library
Oxytocin (OT) and the serotonergic system putatively play important roles in autism spectrum
disorder (ASD) etiology and symptoms, but no direct neurobiological evidence exists for …

Oxytocin's neurochemical effects in the medial prefrontal cortex underlie recovery of task-specific brain activity in autism: a randomized controlled trial

Y Aoki, T Watanabe, O Abe, H Kuwabara… - Molecular …, 2015 - nature.com
The neuropeptide oxytocin may be an effective therapeutic strategy for the currently
untreatable social and communication deficits associated with autism. Our recent paper …