The environmental contaminant inorganic arsenic (iAs) is a human toxicant and carcinogen.
Most mammals metabolize iAs by reducing it to trivalency, followed by oxidative methylation …

Exposure to arsenic (As)-contaminated drinking water affects millions of people worldwide.
Arsenic exposure is associated with skin lesions, skin, lung, kidney and liver cancers …

Chronic exposure to inorganic arsenic (iAs) has been associated with increased risk of
various forms of cancer and of noncancerous diseases. Metabolic conversions of iAs that …

Arsenic (As) is a widely occurring environmental contaminant. To assess human exposures
to As, public health officials and researchers often conduct biomonitoring. Samples of urine …

Background Urinary arsenic metabolites (UAs) are used as biomarkers of exposure and
metabolism. Objectives To characterize inter-and intraindividual variability in UAs in healthy …

The relationship of exposure dose and tissue concentration of parent chemical and
metabolites is a critical issue in cases where toxicity may be mediated by a metabolite or by …

Abstract Inorganic arsenic (In-As) is an established human carcinogen. Methylation to
monomethylarsonate (MMA) and dimethylarsinate (DMA) is believed to be the detoxification …

Background: Concerns for arsenic exposure are not limited to toxic waste sites and massive
poisoning events. Chronic exposure continues to be a major public health problem …

Concerns about the adverse effects of chronic arsenic exposure have focused on
contaminated drinking water and airborne workplace exposures; the risks of naturally …

The relationship of exposure and tissue concentration of parent chemical and metabolites
over prolonged exposure is a critical issue for chronic toxicities mediated by metabolite (s) …