Questions and (some) answers on reactive astrocytes
C Escartin, O Guillemaud, M Carrillo‐de Sauvage - Glia, 2019 - Wiley Online Library
Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes
react to virtually all types of pathological alterations in brain homeostasis by significant …
react to virtually all types of pathological alterations in brain homeostasis by significant …
[HTML][HTML] Elusive roles for reactive astrocytes in neurodegenerative diseases
L Ben Haim, MA Carrillo-de Sauvage… - Frontiers in cellular …, 2015 - frontiersin.org
Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …
response. They become reactive in response to virtually all pathological situations in the …
[HTML][HTML] No longer underappreciated: the emerging concept of astrocyte heterogeneity in neuroscience
Astrocytes are ubiquitous in the central nervous system (CNS). These cells possess
thousands of individual processes, which extend out into the neuropil, interacting with …
thousands of individual processes, which extend out into the neuropil, interacting with …
Signaling pathways in reactive astrocytes, a genetic perspective
W Kang, JM Hébert - Molecular neurobiology, 2011 - Springer
Reactive astrocytes are associated with a vast array of central nervous system (CNS)
pathologies. The activation of astrocytes is characterized by changes in their molecular and …
pathologies. The activation of astrocytes is characterized by changes in their molecular and …
[HTML][HTML] Astrocyte crosstalk in CNS inflammation
M Linnerbauer, MA Wheeler, FJ Quintana - Neuron, 2020 - cell.com
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
[HTML][HTML] Astrocytic modulation of neuronal signalling
SS Purushotham, Y Buskila - Frontiers in Network Physiology, 2023 - frontiersin.org
Neuronal signalling is a key element in neuronal communication and is essential for the
proper functioning of the CNS. Astrocytes, the most prominent glia in the brain play a key …
proper functioning of the CNS. Astrocytes, the most prominent glia in the brain play a key …
Astrocytes: heterogeneous and dynamic phenotypes in neurodegeneration and innate immunity
C Cunningham, A Dunne… - The …, 2019 - journals.sagepub.com
Astrocytes are the most numerous cell type in the brain and perform several essential
functions in supporting neuronal metabolism and actively participating in neural circuit and …
functions in supporting neuronal metabolism and actively participating in neural circuit and …
A stocked toolbox for understanding the role of astrocytes in disease
A Almad, NJ Maragakis - Nature Reviews Neurology, 2018 - nature.com
Our understanding of astrocytes and their role in neurological diseases has increased
considerably over the past two decades as the diverse roles of these cells have become …
considerably over the past two decades as the diverse roles of these cells have become …
Astrocyte diversity: current insights and future directions
T Westergard, JD Rothstein - Neurochemical research, 2020 - Springer
Abstract Astrocytes make up 20–40% of glial cells within the central nervous system (CNS)
and provide several crucial functions, ranging from metabolic and structural support to …
and provide several crucial functions, ranging from metabolic and structural support to …
[HTML][HTML] Astrogliosis as a therapeutic target for neurodegenerative diseases
Chronic neurodegenerative diseases represent major unmet needs for therapeutic
interventions. Recently, the neurocentric view of brain function and disease has been …
interventions. Recently, the neurocentric view of brain function and disease has been …