Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes
react to virtually all types of pathological alterations in brain homeostasis by significant …

Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …

Astrocytes are ubiquitous in the central nervous system (CNS). These cells possess
thousands of individual processes, which extend out into the neuropil, interacting with …

Reactive astrocytes are associated with a vast array of central nervous system (CNS)
pathologies. The activation of astrocytes is characterized by changes in their molecular and …

Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …

Neuronal signalling is a key element in neuronal communication and is essential for the
proper functioning of the CNS. Astrocytes, the most prominent glia in the brain play a key …

Our understanding of astrocytes and their role in neurological diseases has increased
considerably over the past two decades as the diverse roles of these cells have become …

Astrocytes are the most numerous cell type in the brain and perform several essential
functions in supporting neuronal metabolism and actively participating in neural circuit and …

Abstract Astrocytes make up 20–40% of glial cells within the central nervous system (CNS)
and provide several crucial functions, ranging from metabolic and structural support to …

Chronic neurodegenerative diseases represent major unmet needs for therapeutic
interventions. Recently, the neurocentric view of brain function and disease has been …