The feasibility study of non-invasive fetal trisomy 18 and 21 detection with semiconductor sequencing platform
YJ Jeon, Y Zhou, Y Li, Q Guo, J Chen, S Quan… - PloS one, 2014 - journals.plos.org
Objective Recent non-invasive prenatal testing (NIPT) technologies are based on next-
generation sequencing (NGS). NGS allows rapid and effective clinical diagnoses to be …
generation sequencing (NGS). NGS allows rapid and effective clinical diagnoses to be …
Clinical application of massively parallel sequencing‐based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11 105 pregnancies with mixed risk …
S Dan, W Wang, J Ren, Y Li, H Hu, Z Xu… - Prenatal …, 2012 - Wiley Online Library
Objective To report the performance of massively parallel sequencing (MPS) based prenatal
noninvasive fetal trisomy test based on cell‐free DNA sequencing from maternal plasma in a …
noninvasive fetal trisomy test based on cell‐free DNA sequencing from maternal plasma in a …
Performance of a paired-end sequencing-based noninvasive prenatal screening test in the detection of genome-wide fetal chromosomal anomalies
MD Pertile, N Flowers, D Vavrek, D Andrews… - Clinical …, 2021 - academic.oup.com
Abstract Background Noninvasive prenatal tests (NIPTs) detect fetal chromosomal
anomalies with high clinical sensitivity and specificity. We examined the performance of a …
anomalies with high clinical sensitivity and specificity. We examined the performance of a …
Non‐invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies
H Zhang, Y Gao, F Jiang, M Fu, Y Yuan… - … in Obstetrics & …, 2015 - Wiley Online Library
Objectives To report the clinical performance of massively parallel sequencing‐based non‐
invasive prenatal testing (NIPT) in detecting trisomies 21, 18 and 13 in over 140 000 clinical …
invasive prenatal testing (NIPT) in detecting trisomies 21, 18 and 13 in over 140 000 clinical …
Noninvasive prenatal testing using a novel analysis pipeline to screen for all autosomal fetal aneuploidies improves pregnancy management
B Bayindir, L Dehaspe, N Brison, P Brady… - European Journal of …, 2015 - nature.com
Noninvasive prenatal testing by massive parallel sequencing of maternal plasma DNA has
rapidly been adopted as a mainstream method for detection of fetal trisomy 21, 18 and 13 …
rapidly been adopted as a mainstream method for detection of fetal trisomy 21, 18 and 13 …
Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18
ME Norton, H Brar, J Weiss, A Karimi… - American journal of …, 2012 - Elsevier
OBJECTIVE: We sought to evaluate performance of a noninvasive prenatal test for fetal
trisomy 21 (T21) and trisomy 18 (T18). STUDY DESIGN: A multicenter cohort study was …
trisomy 21 (T21) and trisomy 18 (T18). STUDY DESIGN: A multicenter cohort study was …
Noninvasive detection of fetal trisomy 21: systematic review and report of quality and outcomes of diagnostic accuracy studies performed between 1997 and 2012
E Mersy, LJM Smits, LAAP van Winden… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Research on noninvasive prenatal testing (NIPT) of fetal trisomy 21 is
developing fast. Commercial tests have become available. To provide an up-to-date …
developing fast. Commercial tests have become available. To provide an up-to-date …
Clinical experience of non-invasive prenatal chromosomal aneuploidy testing in 190,277 patient samples
H Hu, H Liu, C Peng, T Deng, X Fu… - Current molecular …, 2016 - ingentaconnect.com
Objectives: To detect trisomy 21, 18, and 13 in 190,277 clinical samples from the medical
diagnostic laboratories of ten hospitals. Methods: The study assessed the clinical …
diagnostic laboratories of ten hospitals. Methods: The study assessed the clinical …
Diagnostic accuracy of noninvasive detection of fetal trisomy 21 in maternal blood: a systematic review
EJ Verweij, JME Van Den Oever, MA De Boer… - Fetal diagnosis and …, 2012 - karger.com
Background: Both pregnant women and providers of obstetric care are aware of the rapid
advances in noninvasive prenatal diagnosis (NIPD) of fetal trisomies, and appear to look …
advances in noninvasive prenatal diagnosis (NIPD) of fetal trisomies, and appear to look …
Performance of cell-free DNA sequencing-based non-invasive prenatal testing: experience on 36,456 singleton and multiple pregnancies
M La Verde, L De Falco, A Torella, G Savarese… - BMC medical …, 2021 - Springer
Background This paper describes the clinical practice and performance of cell-free DNA
sequencing-based non-invasive prenatal testing (NIPT) as a screening method for fetal …
sequencing-based non-invasive prenatal testing (NIPT) as a screening method for fetal …