Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications
D Salvemini, SF Kim, V Mollace - American Journal of …, 2013 - journals.physiology.org
The nitric oxide (NO) and cyclooxygenase (COX) pathways share a number of similarities.
Nitric oxide is the mediator generated from the NO synthase (NOS) pathway, and COX …
Nitric oxide is the mediator generated from the NO synthase (NOS) pathway, and COX …
The role of nitric oxide in prostaglandin biology; update
SF Kim - Nitric Oxide, 2011 - Elsevier
The biosynthesis of nitric oxide (NO) and prostaglandin share many similarities. Two major
forms of nitric oxide synthase (NOS) and cyclooxygenase (COX) have been identified …
forms of nitric oxide synthase (NOS) and cyclooxygenase (COX) have been identified …
Regulation of cyclooxygenase enzymes by nitric oxide
D Salvemini - Cellular and Molecular Life Sciences CMLS, 1997 - Springer
Nitric oxide (NO), derived from l-arginine (l-Arg) by the enzyme nitric oxide synthase (NOS)
is involved in the regulation of several important physiological and pathophysiological …
is involved in the regulation of several important physiological and pathophysiological …
Nitric oxide synthase and cyclooxygenase pathways: a complex interplay in cellular signaling
A Sorokin - Current Medicinal Chemistry, 2016 - ingentaconnect.com
The cellular reaction to external challenges is a tightly regulated process consisting of
integrated processes mediated by a variety of signaling molecules, generated as a result of …
integrated processes mediated by a variety of signaling molecules, generated as a result of …
[2] Interactions of nitric oxide with cyclooxygenase: In vitro, ex vivo, and in vivo studies
D Salvemini, JL Masferrer - Methods in enzymology, 1996 - Elsevier
Publisher Summary This chapter discusses the modulation of Cyclooxygenase (COX)
activity by nitric oxide (NO) in in vitro, ex vivo, and in vivo models. NO, derived from L …
activity by nitric oxide (NO) in in vitro, ex vivo, and in vivo models. NO, derived from L …
Nitric oxide activates cyclooxygenase enzymes.
D Salvemini, TP Misko, JL Masferrer… - Proceedings of the …, 1993 - National Acad Sciences
We have evaluated the role of nitric oxide (NO) on the activity of the constitutive and induced
forms of cyclooxygenase (COX; COX-1 and COX-2, respectively). Induction of NO synthase …
forms of cyclooxygenase (COX; COX-1 and COX-2, respectively). Induction of NO synthase …
[HTML][HTML] Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymes
S Cuzzocrea, D Salvemini - Kidney international, 2007 - Elsevier
The nitric oxide (NO) and cyclooxygenase (COX) pathways share a number of similarities.
NO is the mediator generated from the NO synthase (NOS) pathway and COX converts …
NO is the mediator generated from the NO synthase (NOS) pathway and COX converts …
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors
V Mollace, C Muscoli, E Masini, S Cuzzocrea… - Pharmacological …, 2005 - ASPET
The biosynthesis and release of nitric oxide (NO) and prostaglandins (PGs) share a number
of similarities. Two major forms of nitric-oxide synthase (NOS) and cyclooxygenase (COX) …
of similarities. Two major forms of nitric-oxide synthase (NOS) and cyclooxygenase (COX) …
Nitric oxide synthase/COX cross-talk: nitric oxide activates COX-1 but inhibits COX-2-derived prostaglandin production
R Clancy, B Varenika, W Huang, L Ballou… - The Journal of …, 2000 - journals.aai.org
It is recognized that there is molecular cross-talk between the inflammatory mediators NO
and PGs that may regulate tissue homeostasis and contribute to pathophysiological …
and PGs that may regulate tissue homeostasis and contribute to pathophysiological …
Inducible cyclooxygenase and nitric oxide synthase
KK Wu - Advances in pharmacology, 1995 - Elsevier
Publisher Summary Prostaglandin H synthase or cyclooxygenase (COX) and nitric oxide
synthase (NOS) are distinct enzymes encoded by different genes. Their enzymatic …
synthase (NOS) are distinct enzymes encoded by different genes. Their enzymatic …
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