IL17RB and IL17REL Expression Are Associated with Improved Prognosis in HPV-Infected Head and Neck Squamous Cell Carcinomas

Y Sun, MAAK Khan, S Mangiola, AD Barrow - Pathogens, 2023 - mdpi.com
Changes in the cellular secretome are implicated in virus infection, malignancy, and anti-
tumor immunity. We analyzed the association between transcriptional signatures (TS) from …

Prognostic biomarker IL17A correlated with immune infiltrates in head and neck cancer

M Yu, XX Qian, G Li, Z Cheng, Z Lin - World Journal of Surgical Oncology, 2022 - Springer
Background The underlying functions and mechanisms of the Th17 pathway in Head and
neck squamous cell carcinoma (HNSCC) progression and tumor immunology are still …

[HTML][HTML] Interleukin 17 and peripheral IL-17-expressing T cells are negatively correlated with the overall survival of head and neck cancer patients

MH Lee, JTC Chang, CT Liao, YS Chen, ML Kuo… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The presence and clinical significance of interleukin (IL)-17 and IL-17-expressing cells have
recently been studied in several types of cancer, but their correlation to tumor development …

Interleukin-17 expression in the serum and exfoliated cervical cells of patients infected with high-risk oncogenic human papillomavirus

CM Bonin, LZ Almeida-Lugo, AR Dos Santos… - Cytokine, 2019 - Elsevier
Persistent infection by high-risk oncogenic human papillomavirus (HR-HPV) is the main
cause of cervical cancer and its precursor lesions, and both the systemic and local …

[HTML][HTML] IL-12RB1: a novel immune prognostic biomarker for oral squamous cell carcinoma and linked to PD-1/PD-L1 expression in the tumor immune …

Z Chen, Q Chen, S Li, S Tu, Q Chen… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background This study aimed to screen and identify potential immune biomarker to predict
the prognosis of oral squamous cell carcinoma (OSCC). Methods Data of OSCC patient from …

Impact of HPV status on immune responses in head and neck squamous cell carcinoma

HA Qureshi, X Zhu, GH Yang, M Steadele, RH Pierce… - Oral Oncology, 2022 - Elsevier
The main objective of our study was to understand the impact of immune cell composition
and the tumor-reactivity of tumor infiltrating lymphocytes (TIL) in HPV-positive (HPV+) and …

Characterization of immune microenvironment in patients with HPV-positive and negative head and neck cancer

Z Wang, Q Wang, Y Tao, J Chen, Z Yuan, P Wang - Scientific Data, 2023 - nature.com
Human papillomavirus (HPV) status strongly predicts positive clinical outcomes in patients
with head and neck squamous cell cancer (HNSCC); however, the potential reasons have …

Cervical cancer–instructed stromal fibroblasts enhance IL23 expression in dendritic cells to support expansion of Th17 cells

B Walch-Rückheim, R Ströder, L Theobald… - Cancer research, 2019 - AACR
Persistent infection with high-risk human papillomavirus (HPV) is a prerequisite for the
development of cervical cancer. HPV-transformed cells actively instruct their …

Differential impact of IL-10 expression on survival and relapse between HPV16-positive and-negative oral squamous cell carcinomas

CY Chuang, WW Sung, L Wang, WL Lin, KT Yeh… - PLoS …, 2012 - journals.plos.org
Human papillomavirus (HPV) is a risk factor in a subset of oropharyngeal cancer; however,
the contribution of HPV in the malignancy of oral squamous cell carcinomas (OSCC) is not …

Role of interleukin-17 in human papillomavirus infection and associated malignancies

U Sahu, P Khare - Microbial Pathogenesis, 2021 - Elsevier
Human papillomavirus infection is among the leading viral infections in the world, causing
severe mortality and morbidity. The virus mainly targets the female genital tract-cervix, vulva …