The adk gene from Mycobacterium tuberculosis codes for an enzyme of 181 amino acids. A
sequence comparison with 52 different forms of adenylate kinases (AK) suggests that the …

Tuberculosis is the leading cause of death worldwide from a single infectious disease.
Search of new therapeutic tools requires the discovery and biochemical characterization of …

Adenosine kinase from Mycobacterium tuberculosis is the only prokaryotic adenosine
kinase that has been isolated and characterized. The enzyme catalyzes the phosphorylation …

The adenylate kinase from the hyperthermophilic archaean species Sulfolobus
acidocaldarius has been cloned, expressed in Escherichia coli, purified and crystallized …

Ak (adenylate kinase) is a ubiquitous enzyme that catalyses a reversible high‐energy
phosphoryl‐transfer reaction between ATP and AMP to form ADP. In the present study, the …

Adenylate kinases (AKs; EC 2.7. 4.3) are essential members of the NMP kinase family that
maintain cellular homeostasis by the interconversion of AMP, ADP and ATP. AKs play a …

Adenosine kinase (AK) is a purine salvage enzyme that catalyzes the phosphorylation of
adenosine to AMP. In Mycobacterium tuberculosis, AK can also catalyze the …

Sequence comparisons of highly related archaeal adenylate kinases (AKs) from the
mesophilic Methanococcus voltae, the moderate thermophile Methanococcus …

The adenylate kinase (AK) gene from Thermotoga neapolitana, a hyperthermophilic
bacterium, was cloned and overexpressed in Escherichia coli, and the recombinant enzyme …

The method of time-resolved dynamic nonradiative excitation energy transfer (ET) was used
to analyze the proposed domain closure in adenylate kinase (AK). A highly active mutant of …