Controversial effects of vitamin D and related genes on viral infections, pathogenesis, and treatment outcomes

C Lee - Nutrients, 2020 - mdpi.com
Vitamin D (VD) plays an essential role in mineral homeostasis and bone remodeling. A
number of different VD-related genes (VDRG) are required for the metabolic activation of VD …

Immune modulatory effects of vitamin D on viral infections

M Siddiqui, JS Manansala, HA Abdulrahman… - Nutrients, 2020 - mdpi.com
Viral infections have been a cause of mortality for several centuries and continue to
endanger the lives of many, specifically of the younger population. Vitamin D has long been …

Vitamin D and infectious diseases: simple bystander or contributing factor?

PHF Gois, D Ferreira, S Olenski, AC Seguro - Nutrients, 2017 - mdpi.com
Vitamin D (VD) is a fat-soluble steroid essential for life in higher animals. It is technically a
pro-hormone present in few food types and produced endogenously in the skin by a …

The interplay between vitamin D and viral infections

M Teymoori‐Rad, F Shokri, V Salimi… - Reviews in medical …, 2019 - Wiley Online Library
The pleiotropic role of vitamin D has been explored over the past decades and there is
compelling evidence for an epidemiological association between poor vitamin D status and …

The immunologic profile of vitamin D and its role in different immune-mediated diseases: an expert opinion

S Giannini, A Giusti, S Minisola, N Napoli, G Passeri… - Nutrients, 2022 - mdpi.com
Historically, vitamin D is recognized as an essential component for the maintenance of the
musculoskeletal system. The immunomodulatory role of vitamin D in health and disease has …

Vitamin D and the anti-viral state

JA Beard, A Bearden, R Striker - Journal of Clinical Virology, 2011 - Elsevier
Vitamin D has long been recognized as essential to the skeletal system. Newer evidence
suggests that it also plays a major role regulating the immune system, perhaps including …

Can we translate vitamin D immunomodulating effect on innate and adaptive immunity to vaccine response?

PO Lang, R Aspinall - Nutrients, 2015 - mdpi.com
Vitamin D (VitD), which is well known for its classic role in the maintenance of bone mineral
density, has now become increasingly studied for its extra-skeletal roles. It has an important …

Genomic or non-genomic? A question about the pleiotropic roles of vitamin D in inflammatory-based diseases

MF Holick, L Mazzei, S García Menéndez… - Nutrients, 2023 - mdpi.com
Vitamin D (vit D) is widely known for its role in calcium metabolism and its importance for the
bone system. However, various studies have revealed a myriad of extra-skeletal functions …

Does vitamin D protect against respiratory viral infections?

KJ Bryson, AA Nash, M Norval - Epidemiology & Infection, 2014 - cambridge.org
The active form of vitamin D has effects on both innate and adaptive immune responses that
may influence the outcome in many infectious diseases. Observational studies conclusively …

Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer

S Sarkar, M Hewison, GP Studzinski… - Critical reviews in …, 2016 - Taylor & Francis
The discovery of vitamin D receptor (VDR) expression in immune cells has opened up a new
area of research into immunoregulation by vitamin D, a niche that is distinct from its classical …