In the past decade, gene-and cell-based therapies have been translated into clinical
application despite enormous costs for the establishment of an efficient gene therapeutic …

Recent progress in scientific and clinical research has made gene therapy a promising
option for efficient and targeted treatment of several inherited and acquired disorders. One of …

Molecular imaging of gene expression in living subjects is leading to significant advances in
the field of gene therapy. Three different technologies have been utilized for monitoring …

Recent advances in stem cell-based regenerative medicine, cell replacement therapy, and
genome editing technologies (ie CRISPR-Cas 9) have sparked great interest in in vivo cell …

The development of genetically engineered therapeutic cells and the evolution of the field of
gene transfer seem to attract more and more attention as advanced approach with which to …

Cancer is one of the world's most concerning health problems and poses many challenges
in the range of approaches associated with the treatment of cancer. Current understanding …

This chapter introduces the basic principles of molecular-genetic imaging, and summarizes
some applications in preclinical research. Molecular-genetic imaging is a fascinating novel …

In cell-based therapies, cells act as therapeutic agents in their own right. Some cell-based
therapies are old, dating back to the first blood transfusions, ranging through platelet and …

Molecular imaging provides spatial and temporal information on cellular changes that occur
during development and in disease. MRI and optical imaging of reporter genes allows for …

For more than a decade, molecular imaging (MI) has increasingly been used to successfully
image gene expression in living animals, thus making significant contributions to the field of …