Anatomical and Biological Considerations to Determine Resectability in Pancreatic Cancer

IF Rompen, JR Habib, CL Wolfgang, AA Javed - Cancers, 2024 - mdpi.com
Simple Summary Surgical candidacy in the treatment of pancreatic cancer is complex. There
are multiple factors influencing if a patient is a good candidate for surgery with or without …

Current concepts in the surgical management of pancreatic cancer

RM Thomas, SA Ahmad - Surgical Oncology Clinics, 2010 - surgonc.theclinics.com
Pancreatic ductal adenocarcinoma (PDA) is the most common pancreatic malignancy,
comprising approximately 85% of cases. In 2009, it is estimated that more than 34,000 …

Prognosis based definition of resectability in pancreatic cancer: a road map to new guidelines

A Oba, C Croce, P Hosokawa, C Meguid… - Annals of …, 2022 - journals.lww.com
Objective: To identify objective preoperative prognostic factors that are able to predict long-
term survival of patients affected by PDAC. Summary of Background Data: In the modern era …

Editorial on: Moving Beyond Anatomic Criteria for Resectability: Validation of the Anatomical and Biological Definitions of Borderline Resectable Pancreatic Cancer …

A Paniccia, A Zureikat - Annals of Surgical Oncology, 2023 - Springer
The last two decades have witnessed significant advances in surgical techniques and
systemic therapy, accompanied by a more nuanced understanding of the biological diversity …

Surgical treatment of pancreatic ductal adenocarcinoma

S Satoi - Cancers, 2021 - mdpi.com
Oncological pancreatic surgery requires a deep knowledge of multimodal treatment,
accurate preoperative recognition of tumor extension—especially to adjacent major vessels …

Current approaches for the curative-intent surgical treatment of pancreatic ductal adenocarcinoma

M Słodkowski, M Wroński, D Karkocha, L Kraj… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer remains one of the most dreaded cancers worldwide.
The incidence of this relatively rare cancer is increasing by almost 1.0% per year. It is …

Preoperative therapy for pancreatic adenocarcinoma—precision beyond anatomy

YD Seo, MHG Katz - Cancer, 2022 - Wiley Online Library
Despite recent advances in the systemic treatment of gastrointestinal tumors, pancreatic
adenocarcinoma (PDAC) remains a challenging disease, with 5‐year survival just over 10 …

Analysis of predictors of resection and survival in locally advanced stage III pancreatic cancer: does the nature of chemotherapy regimen influence outcomes?

F Bednar, MS Zenati, J Steve, S Winters… - Annals of surgical …, 2017 - Springer
Background Locally advanced unresectable pancreatic cancer (LAPC) historically portends
a poor prognosis. FOLFIRINOX and gemcitabine/nab-paclitaxel have proven effective in the …

Evaluation and proposal of novel resectability criteria for pancreatic cancer established by the Japan Pancreas Society

S Yamada, T Fujii, H Takami, M Hayashi, N Iwata… - Surgery, 2017 - Elsevier
Background The guidelines for the classification of the resectability of pancreatic cancer
established by the National Comprehensive Cancer Network can be difficult to utilize in …

Predicting pancreatic cancer resectability and outcomes based on an objective quantitative scoring system

DAS Toesca, RB Jeffrey, R Von Eyben, EL Pollom… - Pancreas, 2019 - journals.lww.com
Objective To quantitatively assess the probability of tumor resection based on
measurements of tumor contact with the major peripancreatic vessels. Methods This is a …