[HTML][HTML] Protective role of berberine on ulcerative colitis through modulating enteric glial cells–intestinal epithelial cells–immune cells interactions

H Li, C Fan, H Lu, C Feng, P He, X Yang… - … Pharmaceutica Sinica B, 2020 - Elsevier
Ulcerative colitis (UC) manifests as an etiologically complicated and relapsing
gastrointestinal disease. The enteric nervous system (ENS) plays a pivotal role in rectifying …

Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation

J Zhang, J Liu, S Zhu, Y Fang, B Wang, Q Jia… - Acta Pharmacologica …, 2021 - nature.com
Accumulating evidence shows that agents targeting gut dysbiosis are effective for improving
symptoms of irritable bowel syndrome (IBS). However, the potential mechanisms remain …

[HTML][HTML] Berberine in the treatment of ulcerative colitis: A possible pathway through Tuft cells

X Xiong, Z Cheng, F Wu, M Hu, Z Liu, R Dong… - Biomedicine & …, 2021 - Elsevier
Ulcerative colitis (UC) is an inflammatory bowel disease with complex pathogenesis, which
is affected by genetic factors, intestinal immune status and intestinal microbial homeostasis …

Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis

H Li, C Feng, C Fan, Y Yang, X Yang, H Lu, Q Lu… - Cell death & …, 2020 - nature.com
Ulcerative colitis (UC) is a chronic and etiologically refractory inflammatory gut disorder.
Although berberine, an isoquinoline alkaloid, has been revealed to exert protective effects …

[HTML][HTML] Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway

Y Dong, H Fan, Z Zhang, F Jiang, M Li… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disorder of the colon, and it has
become one of the world-recognized medical problems as it is recurrent and refractory …

Berberine regulates Treg/Th17 balance to treat ulcerative colitis through modulating the gut microbiota in the colon

H Cui, Y Cai, L Wang, B Jia, J Li, S Zhao… - Frontiers in …, 2018 - frontiersin.org
Berberine (BBR), an alkaloid isolated from Rhizoma Coptidis, Cortex Phellode, and
Berberis, has been widely used in the treatment of ulcerative colitis (UC). However, the …

Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: impact on intestinal epithelial barrier, gut microbiota …

C Li, G Ai, Y Wang, Q Lu, C Luo, L Tan, G Lin… - Pharmacological …, 2020 - Elsevier
Abstract Berberine (BBR), a naturally-occurring isoquinoline alkaloid isolated from several
Chinese herbal medicines, has been widely used for the treatment of dysentery and colitis …

Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy

C Zhu, K Li, XX Peng, TJ Yao, ZY Wang, P Hu… - Frontiers in …, 2022 - frontiersin.org
Berberine (BBR), an isoquinoline alkaloid extracted from Coptidis Rhizoma, has a long
history of treating dysentery in the clinic. Over the past two decades, the polytrophic …

Berberine ameliorates colonic damage accompanied with the modulation of dysfunctional bacteria and functions in ulcerative colitis rats

Z Liao, Y Xie, B Zhou, B Zou, D Xiao, W Liu… - Applied microbiology …, 2020 - Springer
Intestinal flora imbalance is one of the potential pathogenesis of inflammatory bowel
diseases, and the study aims to discover the effect of berberine on the composition and …

Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats

L Zhu, PQ Gu, H Shen - International Immunopharmacology, 2019 - Elsevier
Background Berberine hydrochloride is one the effective compound among Rhizoma
Coptidis, Cortex Phellodendri, and other plants. There are several clinical functions of …