Are metal-induced hypersensitivities in harbor seals associated with liver function?

A Kakuschke, E Valentine-Thon, S Griesel… - Marine pollution …, 2011 - Elsevier
Environmental exposure to metals is believed to affect marine mammal health adversely
including immunosuppression or acute as well as chronic inflammatory processes leading to …

Immunological Impact of Metals in Harbor Seals (Phoca vitulina) of the North Sea

A Kakuschke, E Valentine-Thon, S Griesel… - … science & technology, 2005 - ACS Publications
Environmental pollutants may affect the immune system of marine mammals in many areas
of the industrialized world. This study provides the first evidence for metal-induced …

[PDF][PDF] Metal sensitivity of marine mammals: a case study of a gray seal (Halichoerus grypus).

A Kakuschke, E Valentine-Thon, S Fonfara… - Marine Mammal …, 2006 - researchgate.net
Marine mammals appear to be good indicators of accumulated hazardous substances in the
marine environment caused mainly by consumption of contaminated fish. Because of their …

Blood metal levels and metal-influenced immune functions of harbour seals in captivity

A Kakuschke, E Valentine-Thon, S Griesel… - Marine Pollution …, 2008 - Elsevier
Immunological blood parameters and the effects of environmental pollutants on the immune
system are important to assess the health status of seals. Animals living permanently in seal …

In vitro exposure of seal peripheral blood leukocytes to different metals reveal a sex-dependent effect of zinc on phagocytic activity

S Pillet, V Lesage, M Hammill, DG Cyr… - Marine pollution …, 2000 - Elsevier
Although the immunotoxicity of heavy metals is well established, evaluation of their potential
immunotoxicity in wildlife species is complicated by variables that could modulate the …

The influence of metal pollution on the immune system a potential stressor for marine mammals in the North Sea

A Kakuschke, A Prange - International Journal of Comparative …, 2007 - escholarship.org
Marine mammals of the North Sea are loaded with metal pollutants. The environmental
exposure induces concentrations bioavailable to immune cells high enough to affect their …

A study of metal concentrations and metallothionein binding capacity in liver, kidney and brain tissues of three Arctic seal species

C Sonne, O Aspholm, R Dietz, S Andersen… - Science of the total …, 2009 - Elsevier
Arctic seals are known to accumulate relatively high concentrations of potential toxic heavy
metals in their vital organs, such as livers and kidneys, as well as in their central nervous …

Heavy metals in marine mammals

K Das, V Debacker, S Pillet… - Toxicology of marine …, 2002 - taylorfrancis.com
During the past few decades, increasing concern about environmental pollution has led to
many investigations on heavy metals and their distribution in the sea, air or biological …

[HTML][HTML] Trace elements in blood of Baltic gray seal pups (Halichoerus grypus) from the Gulf of Riga and their relationship with biochemical and clinical parameters

L Puchades, SE Gallego-Rios, A Di Marzio… - Marine Pollution …, 2022 - Elsevier
Trace elements are pollutants of both natural and anthropogenic origin which can influence
negatively on ecosystem and wildlife health. We evaluated trace element in blood samples …

Metal-Induced Impairment of the Cellular Immunity of Newborn Harbor Seals (Phoca Vitulina)

A Kakuschke, E Valentine-Thon, S Fonfara… - Archives of …, 2008 - Springer
The cellular immunity of newborn harbor seals and the influence of pollutants are rarely
investigated. This study evaluated the lymphocyte proliferation using a lymphocyte …