Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

Long non-coding RNA: a new player in cancer

H Zhang, Z Chen, X Wang, Z Huang, Z He… - Journal of hematology & …, 2013 - Springer
Emerging evidence showed that long non-coding RNAs (lncRNAs) play important roles in a
wide range of biological processes and dysregulated lncRNAs are involved in many …

Long noncoding RNAs in cancer cells

DH Bach, SK Lee - Cancer letters, 2018 - Elsevier
Long noncoding RNA (lncRNA) has recently been investigated as key modulators that
regulate many biological processes in human cancers via diverse mechanisms. LncRNAs …

[HTML][HTML] Roles of oncogenic long non-coding RNAs in cancer development

H Do, W Kim - Genomics & informatics, 2018 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are classified as RNAs that are longer than 200
nucleotides and cannot be translated into protein. Several studies have demonstrated that …

The regulatory role of long noncoding RNAs in cancer

Y Tang, BB Cheung, B Atmadibrata, GM Marshall… - Cancer letters, 2017 - Elsevier
With the advances in genomic analysis technologies, especially next-generation RNA
sequencing, a large number of new transcripts have been discovered, leading to better …

Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer

M Hajjari, A Khoshnevisan, YK Shin - Tumor Biology, 2014 - Springer
Different long non-coding RNAs (lncRNAs) are transcribed within the genome. Although
initially argued to be spurious transcriptional noise, these RNAs play important roles in …

The functional role of long non-coding RNA in human carcinomas

EA Gibb, CJ Brown, WL Lam - Molecular cancer, 2011 - Springer
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets

R Fatima, VS Akhade, D Pal, SMR Rao - Molecular and cellular therapies, 2015 - Springer
Long noncoding RNAs are emerging as key players in various fundamental biological
processes. We highlight the varied molecular mechanisms by which lncRNAs modulate …

[HTML][HTML] Long non-coding RNA in cancer

N Hauptman, D Glavač - International journal of molecular sciences, 2013 - mdpi.com
Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are
emerging as new players in tumorigenesis due to their various functions in transcriptional …

Long non-coding RNAs: the regulatory mechanisms, research strategies, and future directions in cancers

N Gao, Y Li, J Li, Z Gao, Z Yang, Y Li, H Liu… - Frontiers in …, 2020 - frontiersin.org
The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …