Extending prematuration with cAMP modulators enhances the cumulus contribution to oocyte antioxidant defence and oocyte quality via gap junctions

HJ Li, ML Sutton-McDowall, X Wang… - Human …, 2016 - academic.oup.com
STUDY QUESTION Can bovine oocyte antioxidant defence and oocyte quality be improved
by extending the duration of pre-in vitro maturation (IVM) with cyclic adenosine mono …

Presence of cumulus cells during in vitro fertilization protects the bovine oocyte against oxidative stress and improves first cleavage but does not affect further …

AN Fatehi, BAJ Roelen, B Colenbrander, EJ Schoevers… - Zygote, 2005 - cambridge.org
The present study was conducted to evaluate the function of cumulus cells during bovine
IVF. Oocytes within cumulus–oocyte complexes (COCs) or denuded oocytes (DOs) were …

Prematuration with cyclic adenosine monophosphate modulators alters cumulus cell and oocyte metabolism and enhances developmental competence of in vitro …

HT Zeng, D Richani, ML Sutton-McDowall… - Biology of …, 2014 - academic.oup.com
Oocyte in vitro maturation (IVM) is an important assisted reproductive technology and
research tool. The adoption of IVM into routine clinical practice has been hindered by its …

Could oxidative stress influence the in-vitro maturation of oocytes?

CMH Combelles, S Gupta, A Agarwal - Reproductive biomedicine online, 2009 - Elsevier
In the efforts aimed at improving the quality of in-vitro-matured human oocytes, the dynamic
balance and roles of pro-/antioxidants merit further consideration. In-vitromaturation (IVM) is …

[HTML][HTML] Effect of in vitro maturation technique and alpha lipoic acid supplementation on oocyte maturation rate: focus on oxidative status of oocytes

S Zavareh, I Karimi, M Salehnia… - International journal of …, 2016 - ncbi.nlm.nih.gov
Background Therapeutic potential of in vitro maturation (IVM) in infertility is growing with
great promise. Although significant progress is obtained in recent years, existing IVM …

Oxidative stress and reproductive function: oxidative stress and in vitro ageing of the post-ovulatory oocyte: an update on recent advances in the field

JH Martin, B Nixon, SL Cafe, RJ Aitken… - …, 2022 - rep.bioscientifica.com
In brief Post-ovulatory ageing of oocytes leads to poor oocyte and embryo quality as well as
abnormalities in offspring. This review provides an update on the contributions of oxidative …

Protection of porcine oocytes against apoptotic cell death caused by oxidative stress during in vitro maturation: role of cumulus cells

H Tatemoto, N Sakurai, N Muto - Biology of reproduction, 2000 - academic.oup.com
The present study was conducted to examine the protective effect of cumulus cells on oocyte
damage caused by reactive oxygen species (ROS), generated by the hypoxanthine …

The defensive role of cumulus cells against reactive oxygen species insult in metaphase II mouse oocytes

F Shaeib, SN Khan, I Ali, M Thakur… - Reproductive …, 2016 - journals.sagepub.com
We investigated the ability of reactive oxygen species (ROS), such as hydrogen peroxide
(H2O2), hydroxyl radical (· OH), and hypochlorous acid (HOCl), to overcome the defensive …

Redox biology of human cumulus cells: basic concepts, impact on oocyte quality, and potential clinical use

L von Mengden, F Klamt, J Smitz - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Four decades have passed since the first successful human embryo conceived
from a fertilization in vitro. Despite all advances, success rates in assisted reproduction …

Importance of antioxidant supplementation during in vitro maturation of mammalian oocytes

SI Rakha, MA Elmetwally, H El-Sheikh Ali… - Veterinary …, 2022 - mdpi.com
Simple Summary In vitro embryo production (IVEP) is a technology that is widely used in the
field of reproductive biology. The first and most important step of IVEP is termed in vitro …