IL-17 regulates adipogenesis, glucose homeostasis, and obesity
Inflammatory mediators have the potential to impact a surprising range of diseases,
including obesity and its associated metabolic syndrome. In this paper, we show that the …
including obesity and its associated metabolic syndrome. In this paper, we show that the …
IL-17 in obesity and adipogenesis
M Ahmed, SL Gaffen - Cytokine & growth factor reviews, 2010 - Elsevier
The pro-inflammatory cytokine interleukin (IL)-17 (also known as IL-17) has been associated
with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic …
with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic …
IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors
M Ahmed, SL Gaffen - Cytokine, 2013 - Elsevier
IL-17 is an inflammatory cytokine associated with anti-microbial host defense and
pathogenesis of autoimmune diseases. Obesity is considered to be an inflammatory …
pathogenesis of autoimmune diseases. Obesity is considered to be an inflammatory …
Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes
JH Shin, DW Shin, M Noh - Biochemical pharmacology, 2009 - Elsevier
The immune system is closely linked to human metabolic diseases. Serum levels of IL-6
increase with obesity and insulin resistance. Not only does IL-6 decrease the insulin …
increase with obesity and insulin resistance. Not only does IL-6 decrease the insulin …
Inhibition of the IL-17A axis in adipocytes suppresses diet-induced obesity and metabolic disorders in mice
A Teijeiro, A Garrido, A Ferre, C Perna, N Djouder - Nature Metabolism, 2021 - nature.com
Overnutrition causes obesity, a global health problem without any effective therapy. Obesity
is characterized by low-grade inflammation, which predisposes individuals to metabolic …
is characterized by low-grade inflammation, which predisposes individuals to metabolic …
T cell–derived IL-22 amplifies IL-1β–driven inflammation in human adipose tissue: Relevance to obesity and type 2 diabetes
Proinflammatory cytokines are critically involved in the alteration of adipose tissue biology
leading to deterioration of glucose homeostasis in obesity. Here we show a pronounced …
leading to deterioration of glucose homeostasis in obesity. Here we show a pronounced …
Pathogenic role of IL-17-producing immune cells in obesity, and related inflammatory diseases
M Chehimi, H Vidal, A Eljaafari - Journal of clinical medicine, 2017 - mdpi.com
Obesity is associated with low-grade chronic inflammation. Indeed, adipose tissues (AT) in
obese individuals are the former site of progressive infiltration by pro-inflammatory immune …
obese individuals are the former site of progressive infiltration by pro-inflammatory immune …
Interleukin‐15 contributes to the regulation of murine adipose tissue and human adipocytes
NG Barra, S Reid, R MacKenzie, G Werstuck… - …, 2010 - Wiley Online Library
An alarming global rise in the prevalence of obesity and its contribution to the development
of chronic diseases is a serious health concern. Recently, obesity has been described as a …
of chronic diseases is a serious health concern. Recently, obesity has been described as a …
Association between interleukin-15 and obesity: interleukin-15 as a potential regulator of fat mass
AR Nielsen, P Hojman, C Erikstrup… - The Journal of …, 2008 - academic.oup.com
Objective: IL-15 decreases lipid deposition in preadipocytes and decreases the mass of
white adipose tissue in rats, indicating that IL-15 may take part in regulating this tissue. IL-15 …
white adipose tissue in rats, indicating that IL-15 may take part in regulating this tissue. IL-15 …
IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity
J Feng, L Li, Z Ou, Q Li, B Gong, Z Zhao, W Qi… - Cellular & molecular …, 2018 - nature.com
Obesity and associated metabolic diseases are characterized by a chronic low-grade
inflammatory state with the infiltration of many inflammatory cells, especially macrophages …
inflammatory state with the infiltration of many inflammatory cells, especially macrophages …