Background Pneumonia is estimated to cause 2 million deaths every year in children.
Streptococcus pneumoniae is the most important cause of severe pneumonia. We aimed to …

Background When seven-valent pneumococcal conjugate vaccine was introduced in the
USA, many children were vaccinated on schedules that differed from those tested in clinical …

Background Streptococcus pneumoniae is the main cause of invasive bacterial disease in
children aged younger than 2 years. Navajo and White Mountain Apache children have …

Background: Pneumococcus is a leading cause of childhood pneumonia worldwide.
Pneumococcal conjugate vaccines (PCV) have demonstrated efficacy against childhood …

Summary Background Pneumococcal conjugate vaccines (PCVs) are used in many low-
income countries but their impact on the incidence of pneumonia is unclear. The Gambia …

Background Acute respiratory tract infections caused by Streptococcus pneumoniae are a
leading cause of morbidity and mortality in young children. We evaluated the efficacy of a 9 …

Summary Background In March 2010, Brazil introduced the ten-valent pneumococcal
conjugate vaccine (PCV10), which was licensed based on non-inferiority of immunological …

Objective. To evaluate the impact of the introduction and routine use of seven valent
pneumococcal conjugate vaccine on the epidemiology of invasive pneumococcal disease …

Summary Background In 2010, 13-valent pneumococcal conjugate vaccine (PCV13) was
licensed and recommended in the USA for prevention of invasive pneumococcal disease in …

Objective. To determine the effectiveness of the Wyeth heptavalent pneumococcal conjugate
vaccine against clinical and radiograph-confirmed pneumonia in children. Methods. The …