Organophosphorus (OP) compound poisoning is a major global public health problem.
Acute OP insecticide self-poisoning kills over 200,000 people every year, the majority from …

Background: Acute organophosphorus (OP) pesticide poisoning is a major clinical problem
in the developing world. Textbooks ascribe most deaths to respiratory failure occurring in …

Intensive and Respiratory Care, Department of Critical Care, University Medical Centre
Groningen, University of Groningen, PO Box 30001, 9700 RB Groningen, the Netherlands …

The increasing threat of nerve agent use for terrorist purposes against civilian and military
population calls for effective therapeutic preparedness. At present, administration of atropine …

Background: Organophosphorus (OP) pesticides poisoning can result from occupational,
accidental or intentional exposure. Clinical manifestations include cholinergic syndromes …

Organophosphate (OP) poisoning causes a cholinergic crisis with a wide range of clinical
effects including central apnea, pulmonary bronchoconstriction and secretions, seizures …

Objective: Early deaths from organophosphorus (OP) pesticide self‐poisoning result from
respiratory failure and cardiovascular collapse. Therapy requires the urgent use of atropine …

Organophosphate (OP) pesticide poisoning is a global health problem with over 250,000
deaths per year. OPs affect neuronal signaling through acetylcholine (Ach) …

The paper by Aardema and colleagues in this issue of the Netherlands Journal of Medicine
illustrates well the problems that clinicians face with organophosphorus pesticide self …

Organophosphates (OPs) account for a large portion of suicides globally. OP manifests as
cholinergic crises, which underlie respiratory failure. There are many pathways by which …