[HTML][HTML] Formulation, optimization and characterization of allantoin-loaded chitosan nanoparticles to alleviate ethanol-induced gastric ulcer: in-vitro and in-vivo studies
RM Aman, RA Zaghloul, MS El-Dahhan - Scientific reports, 2021 - nature.com
Allantoin (ALL) is a phytochemical possessing an impressive array of biological activities.
Nonetheless, developing a nanostructured delivery system targeted to augment the gastric …
Nonetheless, developing a nanostructured delivery system targeted to augment the gastric …
Novel chitosan oligosaccharide-based nanoparticles for gastric mucosal administration of the phytochemical “apocynin”
Background: Apocynin (APO) is a bioactive phytochemical with prominent anti-inflammatory
and anti-oxidant activities. Designing a nano-delivery system targeted to potentiate the …
and anti-oxidant activities. Designing a nano-delivery system targeted to potentiate the …
In vitro–in vivo evaluation of chitosan-PLGA nanoparticles for potentiated gastric retention and anti-ulcer activity of diosmin
WE Abd El Hady, EA Mohamed… - International journal …, 2019 - Taylor & Francis
Background Diosmin showed poor water solubility and low bioavailability. Poly (d, l-lactide-
co-glycolide)(PLGA) nanoparticles were successfully used to improve the drugs solubility …
co-glycolide)(PLGA) nanoparticles were successfully used to improve the drugs solubility …
Development of famotidine-loaded lecithin-chitosan nanoparticles for prolonged and efficient anti-gastric ulcer activity
MB Zewail, SA El-Gizawy, GF Asaad… - Journal of Drug Delivery …, 2024 - Elsevier
Lecithin-chitosan nanoparticles (LCNPs) represent an appealing nanocarrier for the oral
delivery of hydrophobic drugs. Negatively charged lecithin and positively charged chitosan …
delivery of hydrophobic drugs. Negatively charged lecithin and positively charged chitosan …
Taurine loaded chitosan-pectin nanoparticle shows curative effect against acetic acid-induced colitis in rats
Owing to the poor outcomes and adverse side effects of existing ulcerative colitis drugs, the
study aimed to develop an alternative nano-based treatment approach. The study was …
study aimed to develop an alternative nano-based treatment approach. The study was …
[HTML][HTML] Amoxicillin-docosahexaenoic acid encapsulated chitosan-alginate nanoparticles as a delivery system with enhanced biocidal activities against Helicobacter …
Encapsulation of amoxicillin (AMX) for drug delivery against Helicobacter pylori infection
and aspirin-induced ulcers in rat's stomachs was performed using docosahexaenoic acid …
and aspirin-induced ulcers in rat's stomachs was performed using docosahexaenoic acid …
[HTML][HTML] Gastroprotective chitosan nanoparticles loaded with oleuropein: An in vivo proof of concept
H Abd-Allah, J Youshia, GA Abdel Jaleel, A Hassan… - Pharmaceutics, 2024 - mdpi.com
Oleuropein is the main constituent of olive leaf extract, and it has shown antioxidant and
gastroprotective properties against gastric ulcers. Chitosan nanoparticles are known for their …
gastroprotective properties against gastric ulcers. Chitosan nanoparticles are known for their …
Protective effects of chitosan-bilirubin nanoparticles against ethanol-induced gastric ulcers
Z Huang, Y Shi, H Wang, C Chun, L Chen… - International journal …, 2021 - Taylor & Francis
Purpose Gastric ulcers (GU) are a disease of the gastrointestinal tract that can be caused by
excessive alcohol consumption and heavy use of nonsteroidal anti-inflammatory drugs. GU …
excessive alcohol consumption and heavy use of nonsteroidal anti-inflammatory drugs. GU …
Bletilla striata Polysaccharide Nanoparticles Improved the Therapeutic Efficacy of Omeprazole on the Rat Gastric Ulcer Induced by Ethanol
L Li, J Jing, S Yang, S Fang, W Liu, C Wang… - Molecular …, 2023 - ACS Publications
Gastric ulcers are a common clinical presentation affecting anyone, regardless of their age
or gender. Nanoparticles (NPs) containing Bletilla striata polysaccharide (BSP) and …
or gender. Nanoparticles (NPs) containing Bletilla striata polysaccharide (BSP) and …
[HTML][HTML] Formulation and evaluation of silymarin-loaded chitosan-montmorilloite microbeads for the potential treatment of gastric ulcers
Silymarin-loaded mucoadhesive microbeads of Chitosan-MMT were developed using the
ionotropic gelation technique. Characterization of the microbeads was performed by DSC …
ionotropic gelation technique. Characterization of the microbeads was performed by DSC …