In accordance with “the response to injury” theory, the entry of monocytes into the intima
guided by inflammation signals, taking up cholesterol and transforming into foam cells, and …

Atherosclerosis is a complex inflammatory disease involving cellular migration and
interaction. Vascular injury in response to different cardiovascular risk factors enhances …

The activation of endothelial cells at atherosclerotic lesion–prone sites in the arterial tree
results in the up-regulation of cell adhesion molecules and chemokines, which mediate the …

Monocytes fundamentally contribute to immune surveillance and the inflammatory response
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …

In response to vascular injury, monocytes and smooth muscle cells migrate to the intimal
space, resulting in the formation of atherosclerotic and restenotic lesions. Several different …

Chemokine‐induced leukocyte migration into the vessel wall is an early pathological event
in the progression of atherosclerosis, the underlying cause of myocardial infarction. The …

Accumulation of classical monocytes is imperative for the progression of atherosclerosis.
Hence, therapeutic interference with mechanisms of lesional monocyte recruitment, the …

Atherosclerosis is a progressive chronic disease of large and medium arteries,
characterized by the formation of atherosclerotic plaques. Monocytes and macrophages are …

The Monocyte in Atherosclerosis — Should I Stay or Should I Go Now? | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Recent clinical and experimental evidence indicates that inflam-matory processes in the
vascular wall are the decisive factor that accounts for the rate of lesion formation and clinical …