Spatiotemporal complexity of the aortic sinus vortex

B Moore, LP Dasi - Experiments in fluids, 2014 - Springer
The aortic sinus vortex is a classical flow structure of significant importance to aortic valve
dynamics and the initiation and progression of calcific aortic valve disease. We characterize …

Spatiotemporal complexity of the aortic sinus vortex as a function of leaflet calcification

H Hatoum, LP Dasi - Annals of biomedical engineering, 2019 - Springer
Several studies have shown the variation of aortic sinus structures' hemodynamics with
different flow and geometric characteristics. They have also correlated aortic sinus …

[HTML][HTML] Sinus hemodynamics in representative stenotic native bicuspid and tricuspid aortic valves: an in-vitro study

H Hatoum, LP Dasi - Fluids, 2018 - mdpi.com
(1) The study's objective is to assess sinus hemodynamics differences between stenotic
native bicuspid aortic valve (BAV) and native tricuspid aortic valve (TrAV) sinuses in order to …

Coronary flow impacts aortic leaflet mechanics and aortic sinus hemodynamics

BL Moore, LP Dasi - Annals of biomedical engineering, 2015 - Springer
Mechanical stresses on aortic valve leaflets are well-known mediators for initiating
processes leading to calcific aortic valve disease. Given that non-coronary leaflets calcify …

Aortic valve leaflet wall shear stress characterization revisited: impact of coronary flow

K Cao, P Sucosky - Computer Methods in Biomechanics and …, 2017 - Taylor & Francis
Computational characterizations of aortic valve hemodynamics have typically discarded the
effects of coronary flow. The objective of this study was to complement our previous fluid …

Vorticity dynamics of a bileaflet mechanical heart valve in an axisymmetric aorta

LP Dasi, L Ge, HA Simon, F Sotiropoulos… - Physics of …, 2007 - pubs.aip.org
We present comprehensive particle image velocimetry measurements and direct numerical
simulation (DNS) of physiological, pulsatile flow through a clinical quality bileaflet …

An in vitro study of the onset of turbulence in the sinus of Valsalva.

JA Peacock - Circulation research, 1990 - Am Heart Assoc
During systole a small portion of the mainstream aortic flow is intercepted by the sinus ridge,
or downstream corner of the sinus of Valsalva. This fluid curls back toward the ventricle to …

Effect of left and right coronary flow waveforms on aortic sinus hemodynamics and leaflet shear stress: correlation with calcification locations

DC Flemister, H Hatoum, V Guhan, B Zebhi… - Annals of biomedical …, 2020 - Springer
Coronary flow induces hemodynamic alterations in the aortic sinus region. The objectives of
this study are to:(1) investigate the differences among sinus hemodynamics and leaflet wall …

Mathematical modeling of aortic valve dynamics during systole

Y Aboelkassem, D Savic, SG Campbell - Journal of theoretical biology, 2015 - Elsevier
We have derived a mathematical model describing aortic valve dynamics and blood flow
during systole. The model presents a realistic coupling between aortic valve dynamics, sinus …

[HTML][HTML] Investigation of atrial vortices using a novel right heart model and possible implications for atrial thrombus formation

U Gülan, A Saguner, D Akdis, A Gotschy, R Manka… - Scientific reports, 2017 - nature.com
The main aim of this paper is to characterize vortical flow structures in the healthy human
right atrium, their impact on wall shear stresses and possible implications for atrial thrombus …