Abstract The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human
Cell Atlas, aims to create a comprehensive reference map of cells during development. This …

INTRODUCTION A reference atlas of human cell types is a major goal for the field. Here, we
set out to generate single-cell atlases of both gene expression (this study) and chromatin …

Single-cell gene expression analyses of mammalian tissues have uncovered profound
stage-specific molecular regulatory phenomena that have changed the understanding of …

Comprehensively characterizing the cellular composition and organization of tissues has
been a long-term scientific challenge that has limited our ability to study fundamental and …

To the Editor—Building the Human Cell Atlas (HCA) requires consistent and agile
experimental designs, standardized operating protocols (SOPs), benchmarks and quality …

The early window of human embryogenesis is largely a black box for developmental
biologists. Here we probed the cellular diversity of 4–6 week human embryos when …

Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of
the three germ layers transform into an embryo that includes most of the major internal and …

The Human Cell Atlas: from vision to reality | Nature Skip to main content Thank you for visiting
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International efforts are underway to provide a comprehensive survey of cells across the
human life span (,). These efforts assign cell “types” on the basis of a set of information-rich …

The Human Cell Atlas (HCA) will be made up of comprehensive reference maps of all
human cells-the fundamental units of life-as a basis for understanding fundamental human …