Functional analysis of the superoxide dismutase family in Aspergillus fumigatus

K Lambou, C Lamarre, R Beau, N Dufour… - Molecular …, 2010 - Wiley Online Library
Reactive oxidant species produced by phagocytes have been reported as being involved in
the killing of Aspergillus fumigatus. Fungal superoxide dismutases (SODs) that detoxify …

The Cu, Zn superoxide dismutases of Aspergillus flavus, Aspergillus niger, Aspergillus nidulans, and Aspergillus terreus: purification and biochemical comparison with …

MD Holdom, RJ Hay, AJ Hamilton - Infection and immunity, 1996 - Am Soc Microbiol
Cu, Zn superoxide dismutases (SODs) have been purified to homogeneity from Aspergillus
flavus and A. niger, which are significant causative agents of aspergillosis, and from A …

Production and Characterization of RecombinantAspergillus fumigatus Cu,Zn Superoxide Dismutase and Its Recognition by Immune Human Sera

MD Holdom, B Lechenne, RJ Hay… - Journal of clinical …, 2000 - Am Soc Microbiol
ABSTRACT The Cu, Zn superoxide dismutase (SOD) of Aspergillus fumigatus has
previously been purified and shown to be immunoreactive to the sera of patients with …

The Sho1 Sensor Regulates Growth, Morphology, and Oxidant Adaptation in Aspergillus fumigatus but Is Not Essential for Development of Invasive Pulmonary …

Y Ma, J Qiao, W Liu, Z Wan, X Wang… - Infection and …, 2008 - Am Soc Microbiol
Aspergillus fumigatus is an important opportunistic fungal pathogen. This organism must be
able to adapt to stress changes in the microenvironment during host invasion and systemic …

[HTML][HTML] A cytoplasmic Cu-Zn superoxide dismutase SOD1 contributes to hyphal growth and virulence of Fusarium graminearum

SH Yao, Y Guo, YZ Wang, D Zhang, L Xu… - Fungal Genetics and …, 2016 - Elsevier
Superoxide dismutases (SODs) are scavengers of superoxide radicals, one of the main
reactive oxygen species (ROS) in the cell. SOD-based ROS scavenging system constitutes …

[PDF][PDF] Genes and molecules involved in Aspergillus fumigatus virulence

A Rementeria, N López-Molina, A Ludwig… - Rev Iberoam …, 2005 - reviberoammicol.com
Aspergillus fumigatus causes a wide range of diseases that include mycotoxicosis, allergic
reactions and systemic diseases (invasive aspergillosis) with high mortality rates …

The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence

DE Ejzykowicz, MM Cunha, S Rozental… - Molecular …, 2009 - Wiley Online Library
Aspergillus fumigatus causes serious and frequently fatal infections in immunocompromised
patients. To investigate the regulation of virulence of this fungus, we constructed and …

Fungal responses to reactive oxygen species

J Aguirre, W Hansberg, R Navarro - Medical Mycology, 2006 - academic.oup.com
Reactive oxygen species (ROS) such as hydrogen peroxide, produced externally or during
normal metabolism, can damage different cell components and usually trigger a …

The Aspergillus fumigatus Transcriptional Regulator AfYap1 Represents the Major Regulator for Defense against Reactive Oxygen Intermediates but Is Dispensable …

F Lessing, O Kniemeyer, I Wozniok, J Loeffler… - Eukaryotic …, 2007 - Am Soc Microbiol
Macrophages and neutrophils kill the airborne fungal pathogen Aspergillus fumigatus. The
dependency of this killing process on reactive oxygen intermediates (ROI) has been strongly …

A Regulator of Aspergillus fumigatus Extracellular Proteolytic Activity Is Dispensable for Virulence

A Bergmann, T Hartmann, T Cairns… - Infection and …, 2009 - Am Soc Microbiol
Virulence of the fungal pathogen Aspergillus fumigatus is in part based on the saprophytic
lifestyle that this mold has evolved. A crucial function for saprophytism resides in secreted …