Effect of heart rate on the outcome of renal denervation in patients with uncontrolled hypertension

M Boehm, K Tsioufis, DE Kandzari, K Kario… - Journal of the American …, 2021 - jacc.org
Background Sham-controlled trials demonstrated safety and efficacy of renal denervation
(RDN) to lower blood pressure (BP). Association of baseline heart rate with BP reduction …

Ambulatory heart rate reduction after catheter-based renal denervation in hypertensive patients not receiving anti-hypertensive medications: data from SPYRAL HTN …

M Böhm, F Mahfoud, RR Townsend… - European heart …, 2019 - academic.oup.com
Aims The randomized sham-controlled SPYRAL HTN-OFF MED trial demonstrated that
renal denervation (RDN) using a multi-electrode catheter lowers ambulatory blood pressure …

Safety and efficacy of renal denervation in patients taking antihypertensive medications

DE Kandzari, RR Townsend, K Kario, F Mahfoud… - Journal of the American …, 2023 - jacc.org
Background Renal denervation (RDN) reduces blood pressure (BP) in patients with
uncontrolled hypertension in the absence of antihypertensive medications. Objectives This …

Impact of antihypertensive medication changes after renal denervation among different patient groups: SPYRAL HTN-ON MED

RR Townsend, KC Ferdinand, DE Kandzari, K Kario… - …, 2024 - Am Heart Assoc
BACKGROUND: The SPYRAL HTN-ON MED (Global Clinical Study of Renal Denervation
With the Symplicity Spyral Multi-electrode Renal Denervation System in Patients With …

Impact of renal denervation on 24-hour ambulatory blood pressure: results from SYMPLICITY HTN-3

GL Bakris, RR Townsend, M Liu, SA Cohen… - Journal of the American …, 2014 - jacc.org
Background: Prior studies of catheter-based renal artery denervation have not systematically
performed ambulatory blood pressure monitoring (ABPM) to assess the efficacy of the …

[HTML][HTML] Efficacy and safety of renal denervation for patients with uncontrolled hypertension in Taiwan: 3-year results from the Global SYMPLICITY Registry-Taiwan …

CK Lee, TD Wang, YH Lee, M Fahy, CH Lee… - Acta Cardiologica …, 2019 - ncbi.nlm.nih.gov
Background It is unclear whether renal denervation (RDN) can safely result in blood
pressure (BP) reductions in Asian hypertensive patients and whether such reductions would …

[HTML][HTML] Renal denervation in hypertensive patients not on blood pressure lowering drugs

RL De Jager, MF Sanders, ML Bots, MD Lobo… - Clinical Research in …, 2016 - Springer
Introduction Studies on the blood pressure lowering effect of renal denervation (RDN) in
resistant hypertensive patients have produced conflicting results. Change in medication …

The REDUCE HTN: REINFORCE: randomized, sham-controlled trial of bipolar radiofrequency renal denervation for the treatment of hypertension

MA Weber, AJ Kirtane, MR Weir… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to investigate bipolar radiofrequency renal denervation
in patients with hypertension not receiving medications at baseline. Background A blood …

A systematic review, meta-analysis, and meta regression of the sham controlled renal denervation randomized controlled trials

M Ahmed, M Nudy, R Bussa, A Hajduczok… - Trends in …, 2023 - Elsevier
Renal denervation (RD) has been investigated as a novel blood pressure (BP) lowering
treatment for hypertension. The primary objective of this meta-analysis was to assess the …

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes from the global SYMPLICITY registry

M Böhm, C Ukena, S Ewen, D Linz… - Journal of …, 2016 - journals.lww.com
Objectives: Renal denervation (RDN) can reduce sympathetic activity and blood pressure
(BP) in patients with hypertension. The effects on resting and ambulatory heart rate (HR) …