Subject adherence: are the subjects following the protocol? If not, how to assess and analyze (intention to treat vs. per protocol)

G Ozcan, M Singh, EM Mortensen - Translational Radiation Oncology, 2023 - Elsevier
Subject adherence is a key component of any clinical trial. Poor adherence to interventions
in clinical trials may impair the trials' value, for example, by jeopardizing estimates of a …

When can cancer patient treatment nonadherence be considered intentional or unintentional? A scoping review

L Wreyford, R Gururajan, X Zhou - Plos one, 2023 - journals.plos.org
Background Treatment nonadherence in cancer patients remains high with most
interventions having had limited success. Most studies omit the multi-factorial aspects of …

Subject adherence

K Coffman - Translational Interventional Radiology, 2023 - Elsevier
One of the great struggles of many clinical investigators is the issue of preventing and
correcting for subjects that inevitably deviate from the study protocol. Nonadherence can …

There's many a slip twixt cup and lip: adherence issues in cancer therapy

L Fallowfield - Nature Clinical Practice Oncology, 2008 - nature.com
There's many a slip twixt cup and lip: adherence issues in cancer therapy | Nature Reviews
Clinical Oncology Skip to main content Thank you for visiting nature.com. You are using a …

Assessing the scope and predictors of intentional dose non-adherence in clinical trials

K Getz, Z Smith, L Shafner, A Hanina - Therapeutic Innovation & …, 2020 - Springer
Background Although there is broad agreement that the accurate estimation of non-
adherence rates in clinical trials is essential to determining the dose–response relationship …

Factors influencing non-adherence to radiotherapy: a retrospective audit of 1,548 patients from a tertiary cancer centre

V Palwe, R Patil, P Pandit, R Nagarkar - Journal of Radiotherapy in …, 2020 - cambridge.org
Purpose: To determine the frequency, factors and reasons of patient non-adherence to
radiotherapy (RT) in a tertiary cancer centre. Background: Inadvertent treatment interruptions …

Participant adherence

LM Friedman, CD Furberg, DL DeMets… - Fundamentals of clinical …, 2015 - Springer
The terms compliance and adherence are often used interchangeably. In 1979, Haynes et
al., defined compliance as “the extent to which a person's behavior (in terms of taking …

Promoting treatment adherence

KB Haskard-Zolnierek, TA Miller… - Oxford Textbook of …, 2017 - books.google.com
Patient adherence (also referred to as compliance or concordance) represents the extent to
which a patient follows through with the medical recommendations of the healthcare …

Enhancing adherence in clinical research

WN Robiner - Contemporary clinical trials, 2005 - Elsevier
This article presents overviews of adherence or compliance in clinical care and research,
focusing on the need to enhance research adherence. The scope of the clinical research …

Reasons for radiation therapy nonadherence from the patient's perspective

J Purswani, S Baliga, H Haynes, R Kabarriti… - International Journal of …, 2016 - redjournal.org
Results 1561 incomplete appointments with available reasons for non-adherence were
identified from a total of 728 patients who underwent curative and palliative radiation therapy …