Abstract The fucosyltransferase 8 gene (FUT8) encodes an enzyme that transfers fucose to
the innermost N-acetylglucosamine unit of N-glycan chains. Recent study showed that fut8 …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal fibrotic interstitial lung
disease. Few circulating biomarkers have been identified to have causal effects on IPF …

Fut8 (α1, 6-Fucosyltransferase) heterozygous knock-out (Fut8+/−) mice had an increased
influx of inflammatory cells into the lungs, and this was associated with an up-regulation of …

Abstract α1, 6‐Fucosyltransferase (Fut8) catalyzes the transfer of a fucose residue to N‐
linked oligosaccharides on glycoproteins by means of an α1, 6‐linkage to form core …

Fucosyltransferase 8 (FUT8) encodes a Golgi-localized α1, 6 fucosyltransferase that is
essential for transferring the monosaccharide fucose into N-linked glycoproteins, a process …

Abstract Mammalian α1, 6-fucosyltransferase (FUT8) catalyses the transfer of a fucose
residue from a donor substrate, guanosine 5′-diphosphate-β-l-fucose to the reducing …

Background The pulmonary phenotype in cystic fibrosis (CF) is variable; thus, environmental
and genetic factors likely contribute to clinical heterogeneity. We hypothesized that …

Abstract The core fucosylation (α1, 6-fucosylation) of glycoproteins is widely distributed in
mammalian tissues, and is altered under pathological conditions. To investigate …

The core fucosylation (α1, 6-fucosylation) of glycoproteins is widely distributed in
mammalian tissues, and is altered under pathological conditions. To investigate …

We previously demonstrated that a deficiency in core fucosylation caused by the genetic
disruption of α1, 6-fucosyltransferase (Fut8) leads to lethal abnormalities and the …