In vivo effects of diadenosine polyphosphates on rat renal microcirculation. Background
Diadenosine polyphosphates (APXA) are vasoactive nucleotides that elicit effects via …

Background. We examined for the first time the vascular effects of purinergic agents that
contribute to the regulation of peripheral vascular resistance in human small renal …

In this study, the effects of diadenosine polyphosphates on kidney function were examined.
Intravenous application of diadenosine hexaphosphate (AP6A) led to a significant threefold …

Diadenosine polyphosphates (APnA) are endogenous dinucleoside molecules consisting of
two adenosine moieties linked via their 5′-ribose positions by a variable number of …

Diadenosine polyphosphates (ApnA; n= 3–6) are potent vasoactive agents in isolated
vessels. Information on effects of ApnA in vivo is still limited despite the fact that these …

The purinergic receptor system plays an important role in the regulation of both vascular and
tubular functions within the kidney; however, the release of purinergic agonists other than …

Results The vasoconstrictive response to Ap 4 A was mediated to a large extent to a P 2 X
receptor which could be shown by inhibition with pyridoxal-phosphate-6-azophenyl-2′, 4 …

Diadenosine polyphosphates have differential hemodynamic effects. The role of the
endothelium in the vascular effects of these agonists is still unclear. Primary cultures of rat …

The activation of P2x‐receptors in the rat renal vasculature by dinucleoside polyphosphates
with variable phosphate group chain length (XpnX; X= Adenin (A)/Guanin (G), n= 4–6) was …

The activation of various purinoceptors in rat renal vasculature by P1, P2‐diadenosine
pyrophosphate (Ap2A), P1, P3‐diadenosine triphosphate (Ap3A), P1, P4‐diadenosine …