Solid tumors are complex and unstructured organs that, in addition to cancer cells, also
contain other cell types. Carcinoma-associated fibroblasts (CAFs) represent an important …

Peritoneal dissemination is a frequent metastatic route for cancers of the ovary and
gastrointestinal tract. Tumour cells metastasize by attaching to and invading through the …

During peritoneal metastasis, cancer cells spread from abdominal solid tumors, disseminate
through the peritoneal fluid and attach to and invade through mesothelial cells (MCs) that …

Peritoneal dissemination is the primary metastatic route of ovarian cancer (OvCa), and is
often accompanied by the accumulation of ascitic fluid. The peritoneal cavity is lined by …

Various types of tumors, particularly those originating from the ovary and gastrointestinal
tract, display a strong predilection for the peritoneal cavity as the site of metastasis. The …

Simple Summary Peritoneal mesothelial cells (PMCs) are the first cell layer to encounter
peritoneal tumors, thereby affecting their progression. In the past, PMCs were considered a …

The peritoneal metastatic route of cancer dissemination is shared by cancers of the ovary
and gastrointestinal tract. Once initiated, peritoneal metastasis typically proceeds rapidly in a …

Simple Summary Ovarian cancer has a poor prognosis and tends to develop peritoneal
dissemination. It is becoming increasingly clear that mesothelial cells that cover the …

Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC)
patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the …

Epithelial ovarian cancer (EOC) is believed to cause peritoneum dissemination through
microenvironmental cell‑to-cell communication between the tumor and mesothelium …