Since it is difficult to study the dynamic biological aspects of brain tumour invasion using
histological sections of surgical biopsy and autopsy tissues, various laboratory systems have …

Degree: Dr. Med. DegreeYear: 1993 Institute: Universitetet i Bergen (Norway) Publisher: The
Gade Institute, Department Of Pathology, University Of Bergen, N-5021 Bergen, Norway …

In order to study brain tumor invasion in vitro, previous three-dimensional model systems
have utilized pre-cultured chick heart fragment and rat brain as targets in co-culture with …

Although no single model of the numerous animal models of brain tumors developed in
recent years perfectly represents the spontaneous human tumors, different ones do have …

A system for coculture between normal rat brain fragments and multicellular spheroids of rat
glioma cells is described. The tumor cells were derived from fetal BD IX rats treated …

Cells were injected intracerebrally and subcutaneously into syngeneic mice. The best
differentiated cell line-P560-failed to produce gliomas while transplantation of the least well …

Three cell lines—VMDk P560, P540 and P497—derived from a transplantable spontaneous
murine astrocytoma have been characterised in vitro and in vivo. The cell lines expressed …

Seven human glioblastomas (five small cell glioblastomas [SCG] and two anaplastic
astrocytomas with giant cells (AAI) grown in serial passage in BALB/c nude mice and nude …

This paper reviews the histopathology and cytopathology of a number of experimental
animal brain tumor models to determine their relevance to human neuro-oncology. The …

The need for a large animal tumor model in experimental neuro-oncology led us to re-
evaluate and to modify the transplantable canine glioma of Wodinsky and Walker …