Does a little difference make a big difference? Bovine β-casein A1 and A2 variants and human health—an update

A Cieślińska, E Fiedorowicz, D Rozmus… - International Journal of …, 2022 - mdpi.com
For over 20 years, bovine beta-casein has been a subject of increasing scientific interest
because its genetic A1 variant during gastrointestinal digestion releases opioid-like peptide …

Health-related outcomes of genetic polymorphism of bovine β-casein variants: A systematic review of randomised controlled trials

D Daniloski, NMD Cunha, NA McCarthy… - Trends in Food Science …, 2021 - Elsevier
Background A number of randomised in vivo trials have to date investigated the health
impacts of the genetic variants A1 and A2 of bovine β-casein. The primary difference …

[PDF][PDF] Discussions of effect A1 and A2 milk beta-casein gene on health

AF Demirel, ÇAK Bahattin - proteins, 2018 - vidagratisvivelibre.com
Scientists in developed countries have still discuss the situation of milk A1 and A2. The
controversy is that one group of scientists claim of A1 type a cause of many health problems …

[HTML][HTML] Characterization of the genetic polymorphism linked to the β-casein A1/A2 alleles using different molecular and biochemical methods

V Vigolo, M Franzoi, F Cendron, G Salvadore… - Journal of Dairy …, 2022 - Elsevier
The 2 major subvariants of β-casein (A1 and A2), coded by CSN2 gene, have received great
interest in the last decade both from the scientific community and the dairy sector due to their …

Proportions of A1, A2, B and C β-casein protein variants in retail milk in the UK

I Givens, P Aikman, T Gibson, R Brown - Food chemistry, 2013 - Elsevier
The A1 variant protein of the β-casein family has been implicated in various disease states
although much evidence is weak or contradictory. The primary objective was to measure, for …

Beta-casein gene polymorphism in Serbian Holstein-Friesian cows and its relationship with milk production traits

R Marko, G Uros, V Branislav, M Milan, K Danijela… - Acta …, 2020 - sciendo.com
The most common types of beta-casein in cow's milk are A1 and A2, which differ in one
amino acid. During the gastrointestinal proteolysis of A1 beta-casein in humans this …

Marker-assisted selection of dairy cows for β-casein gene A2 variant

C Sebastiani, C Arcangeli, M Torricelli, M Ciullo… - Italian Journal of Food …, 2022 - itjfs.com
Many studies highlighted potential associations of β-casein A1 with specific human diseases
and a minor digestibility of milk, due to the bioactive peptide β-casomorphin 7 (BCM-7) …

[HTML][HTML] Beneficial effects of milk having A2 β-casein protein: Myth or reality?

SIS Kay, S Delgado, J Mittal, RS Eshraghi, R Mittal… - The Journal of …, 2021 - Elsevier
Diet has been shown to play an important role in maintaining normal homeostasis in the
human body. Milk and milk products are a major component of the Western diet, but their …

Health Implications of Milk Containing β-Casein with the A2 Genetic Variant

SJ Bell, GT Grochoski, AJ Clarke - Critical reviews in food science …, 2006 - Taylor & Francis
Milk from dairy cows has long provided a high quality source of protein and selected
micronutrients such as calcium to most populations. Recently, a relationship between …

Comparative proteomic characterization of bovine milk containing β‐casein variants A1A1 and A2A2, and their heterozygote A1A2

X Wang, Z Yu, X Zhao, R Han, D Huang… - Journal of the …, 2021 - Wiley Online Library
BACKGROUND Genetic variants of β‐casein are cosnidered to affect the components of
milk. However, limited data are available on the bovine protein components correlated with …