Vascular calcification mechanisms: updates and renewed insight into signaling pathways involved in high phosphate-mediated vascular smooth muscle cell …

N Abbasian - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is associated with aging, cardiovascular and renal diseases and
results in poor morbidity and increased mortality. VC occurs in patients with chronic kidney …

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

CM Shanahan, MH Crouthamel, A Kapustin… - Circulation …, 2011 - Am Heart Assoc
Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia

J Voelkl, F Lang, KU Eckardt, K Amann… - Cellular and Molecular …, 2019 - Springer
Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …

[HTML][HTML] The emerging role of phosphate in vascular calcification

CM Giachelli - Kidney international, 2009 - Elsevier
Vascular calcification is recognized as a major contributor to cardiovascular disease (CVD)
in end stage renal disease (ESRD) patients. Susceptibility to vascular calcification is …

Vascular calcification in chronic kidney disease: diversity in the vessel wall

P Dube, A DeRiso, M Patel, D Battepati… - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is one of the major causes of cardiovascular morbidity and
mortality in patients with chronic kidney disease (CKD). VC is a complex process expressing …

[HTML][HTML] Novel insights into vascular calcification

M Ketteler, C Giachelli - Kidney International, 2006 - Elsevier
Vascular calcification is not just a hallmark of uremic arterio-and atherosclerosis, but also a
significant cardiovascular risk factor in patients with chronic kidney disease. In contrast to the …

Regulatory circuits controlling vascular cell calcification

T Sallam, H Cheng, LL Demer, Y Tintut - Cellular and molecular life …, 2013 - Springer
Vascular calcification is a common feature of chronic kidney disease, cardiovascular
disease, and aging. Such abnormal calcium deposition occurs in medial and/or intimal …

Vascular calcification: an important understanding in nephrology

S Zununi Vahed, S Mostafavi… - Vascular health and …, 2020 - Taylor & Francis
Vascular calcification (VC) is a life-threatening state in chronic kidney disease (CKD). High
cardiovascular mortality and morbidity of CKD cases may root from medial VC promoted by …

Vascular calcification—new insights into its mechanism

SJ Lee, IK Lee, JH Jeon - International journal of molecular sciences, 2020 - mdpi.com
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

Vascular calcification in CKD: New insights into its mechanisms

N Ding, Y Lv, H Su, Z Wang, X Kong… - Journal of Cellular …, 2023 - Wiley Online Library
Vascular calcification (VC) is a common complication of chronic kidney disease (CKD) and
contributes to an increased risk of cardiovascular morbidity and mortality. However, effective …