Design and Characterization of Maltoheptaose-b-Polystyrene Nanoparticles, as a Potential New Nanocarrier for Oral Delivery of Tamoxifen
MA Villetti, AR Clementino, I Dotti, PR Ebani, E Quarta… - Molecules, 2021 - mdpi.com
Tamoxifen citrate (TMC), a non-steroidal antiestrogen drug used for the treatment of breast
cancer, was loaded in a block copolymer of maltoheptaose-b-polystyrene (MH-b-PS) …
cancer, was loaded in a block copolymer of maltoheptaose-b-polystyrene (MH-b-PS) …
Tamoxifen citrate-loaded poly(d,l) lactic acid nanoparticles: Evaluation for their anticancer activity in vitro and in vivo
NR Ravikumara, M Bharadwaj… - Journal of …, 2016 - journals.sagepub.com
The optimization of tamoxifen citrate entrapment and its release from biodegradable poly (d,
l) lactic acid nanoparticles are prepared by modified spontaneous emulsification solvent …
l) lactic acid nanoparticles are prepared by modified spontaneous emulsification solvent …
Chitosan-stearic acid based polymeric micelles for the effective delivery of tamoxifen: cytotoxic and pharmacokinetic evaluation
Chitosan is a widely employed polysaccharide with positive zeta-potential and better
tissue/cell adhesion. Its hydrophilicity, high viscosity, and insolubility at physiological pH are …
tissue/cell adhesion. Its hydrophilicity, high viscosity, and insolubility at physiological pH are …
Chitosan nanoparticles for tamoxifen delivery and cytotoxicity to MCF-7 and Vero cells
NR Ravikumara, B Madhusudhan - Pure and Applied Chemistry, 2011 - degruyter.com
In this study, tamoxifen citrate-loaded chitosan nanoparticles (tamoxcL-ChtNPs) and
tamoxifen citrate-free chitosan nanoparticles (tamoxcF-ChtNPs) were prepared by an ionic …
tamoxifen citrate-free chitosan nanoparticles (tamoxcF-ChtNPs) were prepared by an ionic …
Chitosan-palmitic acid based polymeric micelles as promising carrier for circumventing pharmacokinetic and drug delivery concerns of tamoxifen
Being a BCS class II drug and a good substrate for microsomal enzymes, tamoxifen (TAM)
offers a scope for research owing to poor aqueous solubility and compromised …
offers a scope for research owing to poor aqueous solubility and compromised …
Enhanced preclinical efficacy of tamoxifen developed as alginate–cysteine/disulfide bond reduced albumin nanoparticles
A Martinez, E Muniz, I Iglesias, JM Teijon… - International journal of …, 2012 - Elsevier
Tamoxifen (TMX) is the most common clinical choice for the treatment of advanced or
metastatic estrogen-dependent breast cancer. However, research on new challenging …
metastatic estrogen-dependent breast cancer. However, research on new challenging …
Effective cellular internalization, cell cycle arrest and improved pharmacokinetics of Tamoxifen by cholesterol based lipopolymeric nanoparticles
The present study aims at the development of cholesterol based lipopolymeric nanoparticles
for improved entrapment, better cell penetration and improved pharmacokinetics of …
for improved entrapment, better cell penetration and improved pharmacokinetics of …
Non-covalently coated biopolymeric nanoparticles for improved tamoxifen delivery
MT Chevalier, N Rescignano, S Martin-Saldaña… - European polymer …, 2017 - Elsevier
About one-fifth of cancer patients suffer from breast cancer worldwide. Polymeric
nanoparticles play an important role in delivering chemotherapeutic agents in a controlled …
nanoparticles play an important role in delivering chemotherapeutic agents in a controlled …
Actively targeted delivery of tamoxifen through stimuli-responsive polymeric nanoparticles for cancer chemotherapy
N Azimijou, R Karimi-Soflou, A Karkhaneh - Journal of Drug Delivery …, 2023 - Elsevier
Cancer has been one of the main healthcare problems, demanding novel therapeutic
approaches to improve treatment efficiency. Chemotherapy is a primary clinical therapeutic …
approaches to improve treatment efficiency. Chemotherapy is a primary clinical therapeutic …
Tamoxifen-loaded nanoparticles based on a novel mixture of biodegradable polyesters: characterization and in vitro evaluation as sustained release systems
E Pérez, M Benito, C Teijon, R Olmo… - Journal of …, 2012 - Taylor & Francis
Nanoparticles (NP) from mixtures of two poly (d, l-lactide-co-caprolactone)(PLC)
copolymers, PLC 40/60 and PLC 86/14, with poly (d, l-lactide)(PDLLA) and PCL were …
copolymers, PLC 40/60 and PLC 86/14, with poly (d, l-lactide)(PDLLA) and PCL were …