Gene delivery has been extensively investigated for introducing foreign genetic material into
cells to promote expression of therapeutic proteins or to silence relevant genes. This …

Integrating viral gene delivery with engineered biomaterials is a promising strategy to
overcome a number of challenges associated with virus-mediated gene delivery, including …

Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …

Gene therapy is a promising novel method of tissue regeneration by stimulating or inhibiting
key signaling pathways. However, their therapeutic applications in vivo are largely limited by …

Gene delivery has numerous potential applications both clinically and for basic science
research. Non-viral vectors represent the long-term future of gene therapy and biomaterials …

Gene therapy has drawn significant attention over the past two decades for the treatment of
inherited and acquired diseases. Major research efforts have focused on designing suitable …

With the rapid development of nanotechnology in the recent decade, novel DNA and RNA
delivery systems for gene therapy have become available that can be used instead of viral …

The ability to safely and precisely deliver genetic materials to target sites in complex
biological environments is vital to the success of gene therapy. Numerous viral and nonviral …

Gene therapy is a promising form of treatment for those suffering from neurological disorders
or central nervous system (CNS) injury, however, obstacles remain that limit its translational …